Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential.
作者信息
Jacobson K A, van Galen P J, Williams M
机构信息
Laboratory of Bioorganic Chemistry, NIDDK, National Institutes of Health, Bethesda, Maryland 20892.
出版信息
J Med Chem. 1992 Feb 7;35(3):407-22. doi: 10.1021/jm00081a001.
Abstract
摘要
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本文引用的文献
1
Adenosine: The prototypic neuromodulator.
Neurochem Int. 1989;14(3):249-64. doi: 10.1016/0197-0186(89)90051-x.
2
The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart.
J Physiol. 1929 Nov 25;68(3):213-37. doi: 10.1113/jphysiol.1929.sp002608.
3
Coronary and cardiohemodynamic effects of 2-phenylamino-adenosine (CV-1808) in anesthetized dogs and cats.
Arzneimittelforschung. 1980;30(7):1083-7.
4
A purinergic component in the anticonvulsant action of carbamazepine?
Eur J Pharmacol. 1982 Aug 27;82(3-4):195-7. doi: 10.1016/0014-2999(82)90512-x.
5
Sedative and anticonvulsant effects of adenosine analogs in mouse and rat.
J Pharmacol Exp Ther. 1982 Jan;220(1):70-6.
6
Pyrazolo[3,4-d]pyrimidines as adenosine antagonists.
Life Sci. 1984 May 28;34(22):2117-28. doi: 10.1016/0024-3205(84)90310-2.
7
Inhibition by etazolate (SQ 20009) and cartazolate (SQ 65396) of adenosine-stimulated [3H]cAMP formation in [2-3H]adenine-prelabeled vesicles prepared from guinea pig cerebral cortex.
Biochem Pharmacol. 1982 Apr 1;31(7):1441-2. doi: 10.1016/0006-2952(82)90041-7.
8
CGS 8216: receptor binding characteristics of a potent benzodiazepine antagonist.
Life Sci. 1982 Jan 25;30(4):363-72. doi: 10.1016/0024-3205(82)90573-2.
9
Adenosine receptors: targets for future drugs.
J Med Chem. 1982 Mar;25(3):197-207. doi: 10.1021/jm00345a001.
10
Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts.
Biochem Pharmacol. 1981 Feb 15;30(4):325-33. doi: 10.1016/0006-2952(81)90062-9.
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