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[局部皮瓣治疗晚期皮肤恶性肿瘤继发的全层头皮缺损。附21例临床病例]

[Local flaps in the treatment of full thickness scalp defects secondary to advanced cutaneous malignancy. About 21 clinical cases].

作者信息

Belmahi A, Oufkir A-A

机构信息

Service de chirurgie plastique et chirurgie de la main, hôpital Avicenne, 9, rue Ghzaoua, Souissi, Rabat, Maroc.

出版信息

Ann Chir Plast Esthet. 2007 Dec;52(6):569-76. doi: 10.1016/j.anplas.2007.01.002. Epub 2007 Mar 26.

Abstract

SUBJECT

The advanced tumors of the scalp can involve the calvarium, the dura and the cerebral tissue. The medium sized full thickness scalp defects secondary to the excision of such cutaneous malignancy can be successfully treated with local flaps coming from the remaining scalp if these flaps are large and including at least one major pedicle of the scalp. The cranioplasty can be done immediately or secondarily.

PATIENTS AND METHODS

From May 2001 to July 2006, 21 patients aged between 52 and 78 years old, suffering from advanced basal and squamous cell carcinomas with invasion of the calvarium in all cases, the dura in 1 case and the cerebral tissue in 2 cases have benefited from an excision of the scalp and calvarium with a margin between 1 and 3 cm. The secondary defects measured between 9 and 15 cm for the scalp and between 6 and 9 cm for the calvarium. In 1 case, the dura was resected and reconstructed with a fascia lata graft. The flaps used were: a single pedicled transposition flap based on one or two occipital pedicles in 10 cases--a bipedicled transposition flap based on the superficial temporal pedicles in 3 cases and on the frontal and occipital pedicles in 4 cases--a large rotation flap in 4 cases. These flaps were undermined under the galea without any galeotomies. Their donor sites were immediately grafted. The calvarium was reconstructed by a methylmetacrylate implant in 9 cases, simultaneously with these flaps in 4 cases and secondarily in 5 cases.

RESULTS

There were no vascular problems in all these flaps--3 cases of infection in the simultaneous reconstruction of the scalp and calvarium are reported. The two patients with cerebral invasion are deceased 1 year after the surgery. The other patients are still alive without any recurrence or metastasis with a mean follow-up of 36 months.

CONCLUSION

Such complex defects of the tumoral scalp can be reconstructed with large and axial local flaps of the remaining scalp with safety. The cranioplasty has to be delayed.

摘要

主题

头皮晚期肿瘤可累及颅骨、硬脑膜和脑组织。切除此类皮肤恶性肿瘤后产生的中等大小全层头皮缺损,若局部皮瓣来自剩余头皮且面积大并至少包含一个主要头皮蒂,则可成功治疗。颅骨成形术可一期或二期进行。

患者与方法

2001年5月至2006年7月,21例年龄在52至78岁之间的患者,均患有晚期基底细胞癌和鳞状细胞癌,所有病例均侵犯颅骨,1例侵犯硬脑膜,2例侵犯脑组织,均接受了头皮和颅骨切除,切缘为1至3厘米。头皮继发缺损为9至15厘米,颅骨继发缺损为6至9厘米。1例硬脑膜被切除并用阔筋膜移植重建。所用皮瓣包括:10例基于一个或两个枕部蒂的单蒂移位皮瓣;3例基于颞浅动脉蒂、4例基于额部和枕部蒂的双蒂移位皮瓣;4例大旋转皮瓣。这些皮瓣在帽状腱膜下潜行分离,未进行帽状腱膜切开。其供区立即进行植皮。9例患者用甲基丙烯酸甲酯植入物重建颅骨,其中4例与皮瓣同期进行,5例二期进行。

结果

所有这些皮瓣均未出现血管问题,报告了3例头皮和颅骨同期重建时的感染病例。2例脑侵犯患者术后1年死亡。其他患者仍存活,无复发或转移,平均随访36个月。

结论

此类肿瘤性头皮的复杂缺损可用剩余头皮的大型轴型局部皮瓣安全重建。颅骨成形术应推迟进行。

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