Sartipy Ulrik, Albåge Anders, Mattsson Eva, Lindblom Dan
Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden.
Ann Thorac Surg. 2007 Apr;83(4):1303-9. doi: 10.1016/j.athoracsur.2006.11.071.
Functional mitral regurgitation is common in ischemic dilated cardiomyopathy. Edge-to-edge repair is an option for correction and can be performed through the ventriculotomy during surgical ventricular restoration (SVR). This report describes the durability of the edge-to-edge repair without annuloplasty in combination with SVR.
From March 1997 to July 2002, 31 patients with left ventricular aneurysm or ischemic dilated cardiomyopathy and functional ischemic mitral regurgitation grade II (n = 18), III (n = 10), and IV (n = 3) underwent SVR and edge-to-edge repair without annuloplasty with concomitant coronary artery bypass grafting. Long-term valve competence was assessed by echocardiography. Early and late survival and hospital readmission for heart failure were analyzed.
Early mortality was 5 (16%) of 31 patients. At 1, 3, and 5 years, actuarial survival was 77%, 55%, and 48%. The cumulative follow-up was 117 patient-years (4.5 years mean follow-up). Late echocardiograms performed at a mean of 3.1 years postoperatively showed patients had mitral regurgitation at grade 0 (n = 4), I (n = 10), II (n = 9), and III (n = 1). Two patients underwent reoperation owing to grade III-IV recurrent mitral regurgitation. Freedom from hospital readmission or cardiac death was 56% at 1 year and 48% at 3 years.
Combined mitral valve repair and SVR carries high operative risk and long-term prognosis is worse than after SVR alone. The edge-to-edge repair without annuloplasty for functional ischemic mitral regurgitation seems to be fairly durable in conjunction with SVR. To improve results a transventricular annuloplasty may be added.
功能性二尖瓣反流在缺血性扩张型心肌病中很常见。缘对缘修复是一种矫正方法,可在手术性心室修复(SVR)期间通过心室切开术进行。本报告描述了不进行瓣环成形术的缘对缘修复联合SVR的耐久性。
1997年3月至2002年7月,31例患有左心室室壁瘤或缺血性扩张型心肌病且功能性缺血性二尖瓣反流为II级(n = 18)、III级(n = 10)和IV级(n = 3)的患者接受了SVR和不进行瓣环成形术的缘对缘修复,并同期进行冠状动脉旁路移植术。通过超声心动图评估长期瓣膜功能。分析早期和晚期生存率以及因心力衰竭再次入院的情况。
31例患者中有5例(16%)早期死亡。1年、3年和5年的预期生存率分别为77%、55%和48%。累积随访时间为117患者年(平均随访4.5年)。术后平均3.1年进行的晚期超声心动图显示,患者二尖瓣反流程度为0级(n = 4)、I级(n = 10)、II级(n = 9)和III级(n = 1)。2例患者因III - IV级复发性二尖瓣反流接受了再次手术。1年时无再次入院或心源性死亡的生存率为56%,3年时为48%。
二尖瓣修复与SVR联合手术具有较高的手术风险,长期预后比单纯SVR更差。对于功能性缺血性二尖瓣反流,不进行瓣环成形术的缘对缘修复联合SVR似乎具有相当的耐久性。为改善结果,可增加经心室瓣环成形术。