Pascoe R R, Bagust T J
J Reprod Fertil Suppl. 1975 Oct(23):147-50.
Equine coital exanthema can be produced experimentally in stallions by inoculation with an equine herpesvirus (strain 65/61) and be transmitted during coitus with an infected mare. Serological responses to this infection include the production of complement-fixing and serum-neutralizing antibodies which reach maximum levels 14 to 21 days after infection. Complement-fixing antibodies decline rapidly and are usually not detectable by 60 days after infection, whereas serum-neutralizing antibody activity is maintained for at least 1 year. This disparity provides a useful method for the diagnosis of recent infections and estimation of the temporal incidence of infection in groups of mares. It seems likely that clinically normal carrier mares spread the virus on studs where the disease has previously not occurred.
马交媾疹可通过接种马疱疹病毒(65/61株)在种马中进行实验性诱发,并在与受感染母马交配时传播。对这种感染的血清学反应包括产生补体结合抗体和血清中和抗体,这些抗体在感染后14至21天达到最高水平。补体结合抗体迅速下降,通常在感染后60天无法检测到,而血清中和抗体活性至少维持1年。这种差异为诊断近期感染和估计母马群体中感染的时间发生率提供了一种有用的方法。临床正常的携带病毒母马似乎会在以前未发生过该病的种马场传播病毒。