年轻患者前庭神经鞘瘤的管理——与成年患者临床特征及预后的比较
Management of vestibular schwannomas in young patients-comparison of clinical features and outcome with adult patients.
作者信息
Mirzayan M Javad, Gerganov Venelin M, Lüdemann Wolf, Oi Shizuo, Samii Madjid, Samii Amir
机构信息
Department of Neurosurgery, Medizinische Hchschule Hannover, Hannover, Germany.
出版信息
Childs Nerv Syst. 2007 Aug;23(8):891-5. doi: 10.1007/s00381-007-0308-7. Epub 2007 Mar 24.
OBJECTS
Vestibular schwannomas (VS) in young patients are rare. They are regarded to have different biological characteristics. Our objective is to analyze a series of such patients, with respect to their clinical presentation, treatment, and outcome and to compare the results to a matched series of adult patients.
MATERIALS AND METHODS
Retrospective analysis of 20 patients under 21 years of age. All patients underwent surgery via the retrosigmoid approach. The analysis included: age, gender, tumor size, clinical, and neurological pre- and postoperative status including cochlear and facial nerve function, and complications. Statistical comparison of the young patient's data with a series of 200 adult patients previously published by the authors.
CONCLUSIONS
The current study demonstrates that the outcome after surgical management in patients harboring VS does not show any significant difference between young and adult patients.
目的
年轻患者的前庭神经鞘瘤（VS）较为罕见。它们被认为具有不同的生物学特性。我们的目的是分析一系列此类患者的临床表现、治疗及预后情况，并将结果与一组匹配的成年患者进行比较。
材料与方法
对20例21岁以下患者进行回顾性分析。所有患者均采用乙状窦后入路进行手术。分析内容包括：年龄、性别、肿瘤大小、临床及神经学术前和术后状况，包括耳蜗和面神经功能以及并发症。将年轻患者的数据与作者之前发表的一组200例成年患者的数据进行统计学比较。
结论
当前研究表明，患有VS的患者手术治疗后的预后在年轻患者和成年患者之间未显示出任何显著差异。
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