Samii Madjid, Gerganov Venelin, Samii Amir
Department of Neurosurgery, International Neuroscience Institute, Hannover, Germany.
J Neurosurg. 2006 Oct;105(4):527-35. doi: 10.3171/jns.2006.105.4.527.
The aim of this study was to evaluate and present the results of current surgical treatment of vestibular schwannomas (VSs) and to report the refinements in the operative technique.
The authors performed a retrospective study of 200 consecutive patients who had undergone VS surgery over a 3-year period. Patient records, operative reports, follow-up data, and neuroradiological findings were analyzed. The main outcome measures were magnetic resonance imaging, neurological status, patient complaints, and surgical complications. Complete tumor removal was achieved in 98% of patients. Anatomical preservation of the facial nerve was possible in 98.5% of patients. In patients treated for tumors with extension Classes T1, T2, and T3, the rate of facial nerve preservation was 100%. By the last follow-up examination, excellent or good facial nerve function had been achieved in 81% of the cases. By at least 1 year postsurgery, no patients had total facial palsy. In the patients with preserved hearing, the rate of anatomical preservation of the cochlear nerve was 84%. The overall rate of functional hearing preservation was 51%. There was no surgery-related permanent morbidity in this series of patients. Cerebrospinal fluid leakage was diagnosed in 2% of the patients. The mortality rate was 0%.
The goal of VS treatment should be total removal in one stage and preservation of neurological function, as they determine a patient's quality of life. This goal can be safely and successfully achieved using the retrosigmoid approach.
本研究旨在评估并呈现当前前庭神经鞘瘤(VS)手术治疗的结果,并报告手术技术的改进。
作者对连续200例在3年期间接受VS手术的患者进行了回顾性研究。分析了患者记录、手术报告、随访数据和神经放射学检查结果。主要观察指标为磁共振成像、神经状态、患者主诉和手术并发症。98%的患者实现了肿瘤全切。98.5%的患者能够实现面神经的解剖学保留。在治疗T1、T2和T3级扩展型肿瘤的患者中,面神经保留率为100%。在最后一次随访检查时,81%的病例面神经功能达到优良。术后至少1年,无患者出现完全性面瘫。在听力保留的患者中,蜗神经解剖学保留率为84%。功能性听力保留的总体率为51%。在这组患者中无手术相关的永久性并发症。2%的患者诊断为脑脊液漏。死亡率为0%。
VS治疗的目标应是一期全切并保留神经功能,因为它们决定了患者的生活质量。采用乙状窦后入路可安全、成功地实现这一目标。