Jiménez-Hoyuela García J M, Robledo Carmona J, Martínez Del Valle Torres M D, Ortega Lozano S, Delgado García A, Gómez Doblas J J
Servicio de Medicina Nuclear. Hospital Universitario Virgen de la Victoria, Málaga, España.
Rev Esp Med Nucl. 2007 Mar-Apr;26(2):69-76.
To evaluate diagnostic efficacy of rest myocardial perfusion scintigraphy in the detection of acute coronary syndrome in patients with chest pain and non diagnostic electrocardiogram, comparing it with reference techniques, in Emergency Department.
Myocardial perfusion scintigraphy was carried out in 40 patients with those defined characteristics in the Emergency Department, administering the radiopharmaceutical in the next 6 hours after the pain was over. All subjects followed routine diagnostic and treatment management. Final diagnosis of coronary disease was established by coronariography and/or stress perfusion myocardial scintigraphy. Patients were followed up for 9-12 months.
Myocardial perfusion scintigraphy showed a negative predictive value of 96,15 % (CI 95 %: 86.84-100.00). The main limitation of its application was breast and diaphragmatic attenuation phenomenon, given that correction algorithms were not available. Global kappa coefficient was 0.78 when to compared interobserver agreement.
Rest myocardial perfusion scintigraphy is a safe and efficient test in the screening of patients with chest pain suggestive of angor with non-diagnostic ECG in Emergency Department, and also provides prognostic information and risk stratification.
评估静息心肌灌注显像在急诊科对胸痛且心电图无诊断意义患者急性冠状动脉综合征的诊断效能,并与参考技术进行比较。
对急诊科40例具有上述特征的患者进行心肌灌注显像,在疼痛缓解后的6小时内给予放射性药物。所有受试者均遵循常规诊断和治疗管理。通过冠状动脉造影和/或负荷灌注心肌显像确定冠心病的最终诊断。对患者进行9至12个月的随访。
心肌灌注显像的阴性预测值为96.15%(95%置信区间:86.84 - 100.00)。其应用的主要局限性是乳腺和膈肌衰减现象,因为没有校正算法。观察者间一致性比较时的总体kappa系数为0.78。
静息心肌灌注显像对急诊科提示心绞痛但心电图无诊断意义的胸痛患者进行筛查是一种安全有效的检查方法,还能提供预后信息和风险分层。