Mirtsching B C, Freeman D A
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas.
South Med J. 1992 Feb;85(2):196-7. doi: 10.1097/00007611-199202000-00019.
A patient with stage D prostatic cancer but in reasonably good general health was discovered to have adrenal failure and tumor destruction of the adrenal glands. Because prostatic cancer is common and compatible with prolonged survival, we surveyed other patients with stage D prostatic cancer. On initial screening with the cosyntropin test, we found that 5 of 14 patients failed to respond with an increase in serum cortisol of 10 micrograms/dL, suggesting an adrenal failure incidence of 36%. Retesting, however, indicated that probably all of these were false-positive results.
一名患有D期前列腺癌但总体健康状况尚可的患者被发现存在肾上腺功能衰竭以及肾上腺肿瘤破坏。由于前列腺癌较为常见且患者可长期存活，我们对其他D期前列腺癌患者进行了调查。在最初使用促肾上腺皮质激素试验进行筛查时，我们发现14名患者中有5名血清皮质醇升高未达到10微克/分升，提示肾上腺功能衰竭发生率为36%。然而，再次检测表明这些可能均为假阳性结果。
