Kravitz H M, Corcos D M, Hansen G, Penn R D, Cartwright R D, Gianino J
Department of Psychiatry, Rush-Presbyterian-Saint Luke's Medical Center, College of Kinesiology, University of Illinois, Chicago 60680.
Am J Phys Med Rehabil. 1992 Feb;71(1):48-52.
Electromyographic activity was recorded from tibialis anterior during nocturnal polysomnography in six patients with severe spasticity of spinal origin. The patients had a baclofen reservoir system implanted subcutaneously into their lumbar subarachnoid space and were studied for two nights in a double-blind, placebo controlled, crossover design. Tibialis anterior electromyographic activity per hour of sleep was reduced on the night of baclofen infusion. In particular, less electromyographic activity occurred after arousal from sleep.
在夜间多导睡眠监测期间，记录了6例源于脊髓的严重痉挛患者胫前肌的肌电图活动。这些患者皮下植入了巴氯芬储库系统至腰蛛网膜下腔，并在双盲、安慰剂对照、交叉设计中进行了两晚的研究。在巴氯芬输注当晚，每小时睡眠中的胫前肌肌电图活动减少。特别是，睡眠觉醒后的肌电图活动较少。
