Haq A I, Cook L J
Department of Surgery, Royal Free Hospital, London, UK.
Ann R Coll Surg Engl. 2007 Apr;89(3):303-8. doi: 10.1308/003588407X179143.
Nosocomial MRSA infection has become an important healthcare issue. We present 6 cases of MRSA enteritis, acquired following bowel surgery and ileostomy formation.
The data set was obtained from the experience of one consultant surgeon over 6 years in one medical centre. The clinical features and course of six patients that developed MRSA enteritis postoperatively were obtained through review of case notes and laboratory data.
Four male and two female patients (age range, 22-80 years) developed a clinical syndrome postoperatively requiring treatment within the high dependency unit. Three developed respiratory distress syndrome, and one died from multi-organ failure. Exploratory laparotomy carried out in three patients was negative. All patients were MRSA-negative on admission but had swabs positive for MRSA from ileostomy site postoperatively. All of the three patients who had ileostomy effluent cultured for MRSA had positive results.
Fever, abdominal pain, distension and high stoma output in the early postoperative period following bowel surgery should alert the clinician to the possibility of MRSA enteritis. Patients require aggressive resuscitation and culture of ileostomy effluent for MRSA. Exploratory laparotomy has no obvious benefits. As MRSA enteritis has the potential to be a lethally effective disseminator of MRSA, such clinical features should prompt early instigation of appropriate infection control practices.
医院获得性耐甲氧西林金黄色葡萄球菌(MRSA)感染已成为一个重要的医疗问题。我们报告6例MRSA肠炎病例,这些病例均在肠道手术和回肠造口术后发生。
数据集来自一名顾问外科医生在一个医疗中心6年的经验。通过查阅病例记录和实验室数据,获取了6例术后发生MRSA肠炎患者的临床特征及病程。
4例男性和2例女性患者(年龄范围22 - 80岁)术后出现临床综合征,需要在高依赖病房接受治疗。3例出现呼吸窘迫综合征,1例死于多器官功能衰竭。3例患者进行的剖腹探查结果为阴性。所有患者入院时MRSA检测均为阴性,但术后回肠造口部位拭子MRSA检测呈阳性。对3例回肠造口流出物进行MRSA培养的患者,结果均为阳性。
肠道手术后早期出现发热、腹痛、腹胀及高造口排出量,应提醒临床医生注意MRSA肠炎的可能性。患者需要积极复苏,并对回肠造口流出物进行MRSA培养。剖腹探查并无明显益处。由于MRSA肠炎有可能成为MRSA的致命传播源,此类临床特征应促使尽早采取适当的感染控制措施。