Goseki N, Koike M, Yoshida M
First Department of Surgery, Tokyo Medical and Dental University School of Medicine, Japan.
Cancer. 1992 Mar 1;69(5):1088-93. doi: 10.1002/cncr.2820690503.
Unlike the stomach, the esophageal mucosal layer has abundant vessels. To study the histopathologic character of cancer of the esophagus in comparison with that of stomach, the histologic findings (such as vascular or lymphatic permeation and lymph nodal involvement of cancer) were surveyed in 52 lesions of superficial esophageal carcinoma in which carcinoma invasion was limited to the submucosal layer, 448 cases of so-called early gastric carcinoma in which the carcinoma invasion was limited to the submucosal layer, and 109 cases of gastric carcinoma invading the proper muscle layer (PM-carcinoma). With respect to lymph node metastasis and lymphatic and vascular permeation, there was a particularly high incidence of carcinoma extending to the submucosal layer (SM-carcinoma) of the esophagus and a similar high incidence of PM-carcinoma of the stomach. Carcinoma limited to the mucosal epithelium and mucosal layer of the esophagus (MM-carcinoma) has an incidence similar to carcinoma in the mucous membrane and SM-carcinoma of the stomach, respectively. Thus, the cases in which carcinoma invasion was limited to the muscle layer of the mucosa of the esophagus were shown to have a prognosis similar to that of so-called early carcinoma of the stomach.
与胃不同，食管黏膜层血管丰富。为了对比食管癌与胃癌的组织病理学特征，我们对52例癌浸润局限于黏膜下层的浅表食管癌病变、448例癌浸润局限于黏膜下层的所谓早期胃癌以及109例癌浸润至固有肌层的胃癌（PM癌）的组织学表现（如癌的血管或淋巴管浸润及淋巴结受累情况）进行了调查。关于淋巴结转移以及淋巴管和血管浸润，癌累及食管黏膜下层（SM癌）的发生率特别高，而胃癌的PM癌发生率也同样高。局限于食管黏膜上皮和黏膜层的癌（MM癌）的发生率分别与胃黏膜癌和SM癌相似。因此，癌浸润局限于食管黏膜肌层的病例显示出与所谓早期胃癌相似的预后。
