Setaro J F, Cleman M W, Remetz M S
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Cardiol Clin. 1992 Feb;10(1):165-83.
The right ventricle is frequently affected by pulmonary arterial hypertension of postcapillary obstructive origin. The disorders that cause states of pulmonary venous hypertension arise in the left ventricle, left atrium, or pulmonary veins. Biochemical factors, the pericardium, interventricular septum, and pulmonary arterial system combine to communicate the effects of these disorders to the right ventricle. Although not ideally suited to pressure loading, the right ventricle undergoes a series of structural and hemodynamic adaptations that allow for chronic compensation until failure supervenes, with characteristic clinical findings. Exercise may serve to magnify the abnormalities of right ventricular function. Correction of left-sided heart lesions with improvement in pulmonary venous hypertension is associated with favorable effects on the right ventricle. In states of left-sided heart failure, the level of right ventricular function may provide important prognostic information.
右心室常受毛细血管后阻塞性肺动脉高压影响。导致肺静脉高压状态的疾病发生于左心室、左心房或肺静脉。生化因素、心包、室间隔和肺动脉系统共同作用，将这些疾病的影响传递至右心室。尽管右心室并不十分适合承受压力负荷，但它会经历一系列结构和血流动力学适应过程，从而实现慢性代偿，直至发生衰竭，并出现特征性临床表现。运动可能会加剧右心室功能异常。纠正左侧心脏病变并改善肺静脉高压，对右心室有积极影响。在左侧心力衰竭状态下，右心室功能水平可能提供重要的预后信息。
