恶性胸膜间皮瘤：一级亲属中的两例病例

Malignant pleural mesothelioma: two cases in first degree relatives.

作者信息

Wilkins Anna, Popat Sanjay, Hughes Sarah, O'Brien Mary

机构信息

Department of Medical Oncology, Royal Marsden Hospital, Sutton, SURREY SM2 5PT, United Kingdom.

出版信息

Lung Cancer. 2007 Sep;57(3):407-9. doi: 10.1016/j.lungcan.2007.02.005. Epub 2007 Apr 2.

DOI:10.1016/j.lungcan.2007.02.005

PMID:17400330

Abstract

We report two cases of malignant pleural mesothelioma in first degree relatives arising within weeks of each other. The patients had a shared exposure to asbestos and age difference of over 20 years at time of presentation. In both cases, the anatomical pattern was similar and unusual for mesothelioma and initial histology was reported for both as non-small cell lung cancer. Both patients were treated with platinum-based combination chemotherapy.

摘要

我们报告了两例一级亲属患恶性胸膜间皮瘤的病例，二者发病时间相隔数周。这两名患者都曾接触过石棉，就诊时年龄相差20多岁。两例病例的解剖学模式相似，对于间皮瘤来说都不常见，且最初的组织学报告均为非小细胞肺癌。两名患者均接受了铂类联合化疗。