Shah Sonia S, Karnak Demet, Shah Shetal N, Budev Marie, Machuzak Michael, Gildea Thomas R, Mehta Atul C
Department of Pulmonary, Allergy and Critical Care Medicine, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
J Heart Lung Transplant. 2007 Apr;26(4):407-10. doi: 10.1016/j.healun.2007.01.014.
A broncholith is a calcified lymph node that erodes into and partially or completely obstructs the bronchial lumen. The natural history of broncholiths is poorly understood. They are frequently encountered in residents of areas that are endemic for Histoplasma capsulatum and Mycobacterium tuberculum. We report the first case of a broncholith in which the fungus Histoplasma capsulatum was transferred from a donor to a lung transplant (LTx) recipient. Our report highlights the time course of broncholith development and its successful management. We suspect that broncholithiasis and transmission of Histoplasma capsulatum from a donor to the recipient are under-reported in the LTx literature. We hypothesize that histoplasmosis can be transmitted from the donor to the recipient and the duration in the formation of calcification of the lymph node or the broncholith can be anywhere from 2 to 10 months.
支气管结石是一种钙化的淋巴结，它侵蚀并部分或完全阻塞支气管腔。支气管结石的自然病程尚不清楚。在荚膜组织胞浆菌和结核分枝杆菌流行地区的居民中经常发现支气管结石。我们报告了首例支气管结石病例，其中荚膜组织胞浆菌从供体转移到肺移植（LTx）受者体内。我们的报告强调了支气管结石形成的时间过程及其成功的治疗。我们怀疑在肺移植文献中，支气管结石症和荚膜组织胞浆菌从供体传播到受者的情况报道不足。我们推测组织胞浆菌病可从供体传播到受者，淋巴结或支气管结石钙化形成的持续时间可为2至10个月。
