• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Trial of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) in advanced bronchogenic carcinoma 1,2,3.

作者信息

Stolinsky D C, Bull F E, Pajak T F, Bateman J R

出版信息

Oncology. 1975;31(5-6):288-92. doi: 10.1159/000225035.

DOI:10.1159/000225035
PMID:174040
Abstract

A total of 103 patients with lung cancer was treated with CCNU 130 mg/m2 orally every 6 weeks; 65 patients survived at least 6 weeks. Partial responses occurred in 7 patients. Leukopenia, thrombocytopenia, and nausea were frequent toxic effects. CCNU has slight efficacy in advanced lung cancer. No increase in survival was attributed to therapy.

摘要

相似文献

1
Trial of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) in advanced bronchogenic carcinoma 1,2,3.
Oncology. 1975;31(5-6):288-92. doi: 10.1159/000225035.
2
A combination of adriamycin, CCNU and hydroxyurea in the treatment of disseminated bronchogenic carcinoma.
Eur J Cancer (1965). 1975 Nov;11(11):795-9. doi: 10.1016/0014-2964(75)90173-5.
3
CCNU-adriamycin therapy in bronchogenic carcinoma.
Cancer. 1978 May;41(5):1704-9. doi: 10.1002/1097-0142(197805)41:5<1704::aid-cncr2820410508>3.0.co;2-e.
4
Effect of CCNU (NSC-79037) on bronchogenic carcinoma.
J Natl Cancer Inst. 1973 Jan;50(1):49-53. doi: 10.1093/jnci/50.1.49.
5
Combination chemotherapy with CCNU (NSC-79037),hexamethylmelamine (NSC-13875) and methotrexate (NSC-740) in advanced bronchogenic carcinoma.CCNU（NSC - 79037）、六甲蜜胺（NSC - 13875）和甲氨蝶呤（NSC - 740）联合化疗用于晚期支气管癌。
Oncology. 1975;32(2):82-5. doi: 10.1159/000225054.
6
Mechlorethamine (NSC-762) plus CCNU (NSC-79037) in the treatment of inoperable squamous and large cell carcinoma of the lung.氮芥（NSC - 762）联合洛莫司汀（NSC - 79037）治疗无法手术的肺鳞状细胞癌和大细胞癌
Cancer Treat Rep. 1976 May;60(5):625-7.
7
A clinical trial of CCNU (1-(2 chloroethyl)-3-cyclohexyl-1-nitrosourea) (NSC 79037) in advanced ovarian carcinoma.
J Surg Oncol. 1975;7(5):347-50. doi: 10.1002/jso.2930070504.
8
Study of methyl-CCNU(NSC-95441) in the treatment of lung cancer.甲环亚硝脲（NSC-95441）治疗肺癌的研究。
Cancer Chemother Rep. 1973 Nov-Dec;57(4):419-22.
9
Phase II study of the effect of methyl-CCNU (NSC-95441) on bronchogenic carcinoma.
Cancer Chemother Rep 3. 1973 Mar;4(2):257-9.
10
Combination chemotherapy of advanced lung cancer: a randomized trial.晚期肺癌的联合化疗：一项随机试验。
Cancer. 1976 Dec;38(6):2201-7. doi: 10.1002/1097-0142(197612)38:6<2201::aid-cncr2820380602>3.0.co;2-4.

引用本文的文献

1
Single-agent chemotherapy for advanced adenocarcinoma of the lung. A review.晚期肺腺癌的单药化疗。综述。
Cancer Chemother Pharmacol. 1988;21(2):89-102. doi: 10.1007/BF00257354.