Trial of 1-(2-chloroethyl)-3-cyclohexyl-1-nitrosourea (CCNU; NSC-79037) in advanced bronchogenic carcinoma 1,2,3.
作者信息
Stolinsky D C, Bull F E, Pajak T F, Bateman J R
出版信息
Oncology. 1975;31(5-6):288-92. doi: 10.1159/000225035.
PMID:174040
Abstract
A total of 103 patients with lung cancer was treated with CCNU 130 mg/m2 orally every 6 weeks; 65 patients survived at least 6 weeks. Partial responses occurred in 7 patients. Leukopenia, thrombocytopenia, and nausea were frequent toxic effects. CCNU has slight efficacy in advanced lung cancer. No increase in survival was attributed to therapy.
摘要
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