Wilson W L, Ryzin J V, Weiss A J, Frelick R W, Moss S E
Oncology. 1975;31(5-6):293-309. doi: 10.1159/000225036.
A phase III study was designed comparing the effectiveness of Hexamethyl-melamine (NSC 13875) to Dibromodulcitol (NSC 104800) in lung carcinoma. 250 of the 316 patients entered on the study were stratified into groups according to stage of disease and cell type. The results showsed Hexamethylmelamine to be more effective in patients with squamous cell carcinoma and slightly superior to Dibromodulcitol in patients with anaplastic/undifferentiated cell carcinoma, whereas Dibromodulcitol proved to be more effective in patients with adenocarcinoma.
一项三期研究旨在比较六甲蜜胺（NSC 13875）与二溴卫矛醇（NSC 104800）对肺癌的疗效。参与该研究的316例患者中有250例根据疾病分期和细胞类型进行了分组。结果显示，六甲蜜胺对鳞状细胞癌患者更有效，在间变/未分化细胞癌患者中略优于二溴卫矛醇，而二溴卫矛醇对腺癌患者更有效。
