Tanaka Sakae
The University of Tokyo, Department of Orthopaedic Surgery, Faculty of Medicine.
Clin Calcium. 2007 Apr;17(4):586-92.
Rheumatoid arthritis (RA) is a chronic inflammatory disorder characterized progressive joint destruction. Recent studies have revealed an essential role of receptor activator of NF-kappaB ligand (RANKL) in bone destruction in RA, and therapeutics targeting RANKL has been attracting a great deal of attention.
类风湿关节炎（RA）是一种以进行性关节破坏为特征的慢性炎症性疾病。最近的研究揭示了核因子κB受体活化因子配体（RANKL）在类风湿关节炎骨破坏中的关键作用，针对RANKL的治疗方法一直备受关注。
