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急性胆管炎时CA19-9极度升高。

Extremely elevated CA19-9 in acute cholangitis.

作者信息

Sheen-Chen Shyr-Ming, Sun Cheuk-Kwan, Liu Yei-Wei, Eng Hock-Liew, Ko Sheung-Fat, Kuo Chung-Huang

机构信息

Department of Surgery, Chang Gung Memorial Hospital, Kaohsiung, 123, Ta-Pei Road, Niao-Sung Hsiang, Kaohsiung Hsien, Taiwan.

出版信息

Dig Dis Sci. 2007 Nov;52(11):3140-2. doi: 10.1007/s10620-006-9164-7. Epub 2007 Apr 3.

DOI:10.1007/s10620-006-9164-7
PMID:17404889
Abstract

A 68-year-old women was admitted with the chief complaints of epigastralgia with radiation to the back and jaundice. Fever and chills were also noted. The laboratory data showed alkaline phosphatase, 245 U/L (normal range: 28-94); Direct Bilirubin, 5.29 mg% (0-0.4); Total Bilirubin, 8.4 mg% (0.2-1.4). Surprisingly, the serum CA19-9 was 5673.8 U/ml (normal value: <37). Abdominal sonography showed dilated common hepatic duct. MRCP demonstrated diffuse biliary tree dilatation with a very low signal intensity in distal common bile duct. Surgical intervention reveled a black stone at distal common bile duct and was successfully retrieved. After operation, the CA19-9 fell to 63.1 u/ml two weeks later and returned to normal (10.4 U/ml) one month later.

摘要

一名68岁女性因上腹部疼痛并向后背部放射以及黄疸为主诉入院。还注意到有发热和寒战。实验室检查数据显示:碱性磷酸酶245 U/L(正常范围:28 - 94);直接胆红素5.29 mg%(0 - 0.4);总胆红素8.4 mg%(0.2 - 1.4)。令人惊讶的是,血清CA19 - 9为5673.8 U/ml(正常值:<37)。腹部超声显示肝总管扩张。磁共振胰胆管造影(MRCP)显示胆管树弥漫性扩张,胆总管远端信号强度极低。手术干预发现胆总管远端有一颗黑色结石,并成功取出。术后,CA19 - 9在两周后降至63.1 u/ml,一个月后恢复正常(10.4 U/ml)。

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Elevated tumor-associated antigen CA 19-9 in a patient with an enlarged pancreas: does it always imply malignancy?一名胰腺肿大患者的肿瘤相关抗原CA 19-9升高:这是否总是意味着恶性肿瘤?
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