Payne Heather A, Gillatt David A
Clinical Oncology, University College Hospital, London, UK.
BJU Int. 2007 Mar;99(3):545-53. doi: 10.1111/j.1464-410X.2006.06651.x.
To determine the management practices used by UK oncologists and urologists for patients with locally advanced (non-metastatic) prostate cancer.
Using a postal questionnaire, 155 practising specialist oncologists and urologists were surveyed in the UK. Their views were sought on a multidisciplinary approach to the management of locally advanced prostate cancer and their current management practices.
Over half of respondents recognized the need for both oncologists and urologists to take the lead in management decisions, but almost as many still expected the sole responsibility to lie within their own speciality. Radical radiotherapy (RT) was considered the current optimum treatment by most respondents, but 22% of urologists thought that radical prostatectomy is optimal. Most responders would use luteinizing hormone-releasing hormone agonists as neoadjuvant and adjuvant to RT but there was significant variation in the favoured duration of treatment of these drugs, and in the dose of RT.
This survey suggests that there are still wide variations in the management practices for locally advanced prostate cancer in the UK, and between urologists and oncologists. Improved consensus guidelines are required.
确定英国肿瘤学家和泌尿科医生针对局部晚期（非转移性）前列腺癌患者所采用的管理方法。
通过邮寄问卷调查对英国155名在职专科肿瘤学家和泌尿科医生进行了调查。征求了他们对于局部晚期前列腺癌管理的多学科方法以及他们当前管理方法的意见。
超过半数的受访者认识到肿瘤学家和泌尿科医生都需要在管理决策中发挥主导作用，但几乎同样多的人仍然期望唯一的责任在于他们自己的专业领域。大多数受访者认为根治性放疗（RT）是当前的最佳治疗方法，但22%的泌尿科医生认为前列腺根治术是最佳方法。大多数受访者会使用促黄体激素释放激素激动剂作为RT的新辅助和辅助治疗，但这些药物的首选治疗持续时间以及RT剂量存在显著差异。
这项调查表明，在英国，局部晚期前列腺癌的管理方法在泌尿科医生和肿瘤学家之间仍存在很大差异。需要改进共识指南。
