Weiss R J, Broström E, Stark A, Wick M C, Wretenberg P
Department of Molecular Medicine and Surgery, Karolinska Institutet 171 76 Stockholm, Sweden.
Rheumatology (Oxford). 2007 Jun;46(6):1024-8. doi: 10.1093/rheumatology/kem017. Epub 2007 Apr 4.
To evaluate the effects of ankle/hindfoot arthrodesis in rheumatoid arthritis (RA) patients on gait pattern of the knee and hip.
In this prospective follow-up study, 14 RA patients scheduled for ankle/hindfoot arthrodesis (talo-calcaneal, talo-navicular, calcaneo-cuboid and/or talo-crural joints) and 14 age- and sex-matched healthy controls were included. Three-dimensional gait analyses of joint angles, moments and work were performed at the index operation and after 13 months of follow-up. Each patient underwent clinical assessments of pain while walking, overall evaluation of disease activity, Health Related Quality of Life Questionnaire (EQ-5D), activity limitations, maximum walking distance, difficulty with walking surface and gait abnormality. For comparisons of pre- vs post-operative conditions, Wilcoxon's matched pairs test and Friedman ANOVA by rank test were used.
At follow-up after ankle/hindfoot fusion surgery, RA patients demonstrated a statistically significant improvement in mean range of joint motions, moments and work in the overlying joints such as the knee and hip. Moreover, there was significantly less pain, disease activity, activity limitation, difficulty with walking surface and gait abnormality. EQ-5D and maximum walking distance were also significantly improved at follow-up.
Our results demonstrate that ankle/hindfoot arthrodesis in RA is an effective intervention to reduce pain and to improve Health Related Quality of Life and functional ability. Moreover, the overlying leg joints experience an improvement in joint motion, muscle-generated joint moments and work during walking. Three-dimensional gait analysis may assist future investigations of the effects of orthopaedic surgery on functional mobility in RA to prevent irreversible disablement.
评估类风湿关节炎(RA)患者行踝关节/后足关节融合术对膝关节和髋关节步态模式的影响。
在这项前瞻性随访研究中,纳入了14例行踝关节/后足关节融合术(距下关节、距舟关节、跟骰关节和/或胫距关节)的RA患者以及14名年龄和性别匹配的健康对照者。在初次手术时及随访13个月后进行关节角度、力矩和功的三维步态分析。对每位患者进行了行走时疼痛的临床评估、疾病活动度的总体评估、健康相关生活质量问卷(EQ-5D)、活动受限情况、最大行走距离、行走路面困难程度和步态异常情况的评估。对于术前与术后情况的比较,采用Wilcoxon配对检验和Friedman秩和检验。
在踝关节/后足融合手术后的随访中,RA患者在上覆关节如膝关节和髋关节处的平均关节活动范围、力矩和功有统计学意义的显著改善。此外,疼痛、疾病活动度、活动受限、行走路面困难程度和步态异常情况明显减轻。随访时EQ-5D和最大行走距离也有显著改善。
我们的结果表明,RA患者行踝关节/后足关节融合术是一种有效的干预措施,可减轻疼痛,改善健康相关生活质量和功能能力。此外,上覆的腿部关节在行走时的关节活动、肌肉产生的关节力矩和功均有改善。三维步态分析可能有助于未来对骨科手术对RA患者功能活动影响的研究,以预防不可逆的残疾。