从基纳微齿叶柃根部分离得到的两种新喹啉和三（4-羟基肉桂酰）精胺衍生物。

Two new quinoline and tris(4-hydroxycinnamoyl)spermine derivatives from Microdesmis keayana roots.

作者信息

Zamble Alexis, Hennebelle Thierry, Sahpaz Sevser, Bailleul François

机构信息

Laboratoire de Pharmacognosie, EA 1043, Faculté des Sciences Pharmaceutiques et Biologiques, Université de Lille 2, France.

出版信息

Chem Pharm Bull (Tokyo). 2007 Apr;55(4):643-5. doi: 10.1248/cpb.55.643.

DOI:10.1248/cpb.55.643

PMID:17409563

Abstract

Purification of a Microdesmis keayana hydromethanolic root extract led to the isolation of two new natural compounds, xanthoquininamide (6-hydroxyquinoline-4-carboxamide) and tris(4-hydroxycinnamoyl)spermine (N(5)-(p-coumaroyl)-N(1),N(14)-diferuloylspermine) which was named keayanine. Their structures were determined using spectroscopic analyses (ESI-MS, 1D- and 2D-NMR).

摘要

对微齿叶柃水甲醇根提取物进行纯化，得到了两种新的天然化合物，即黄喹啉酰胺（6-羟基喹啉-4-甲酰胺）和三（4-羟基肉桂酰）精胺（N(5)-(对香豆酰)-N(1),N(14)-二阿魏酰精胺），后者被命名为微齿叶柃碱。通过光谱分析（电喷雾电离质谱、一维和二维核磁共振）确定了它们的结构。