Mac Manus Michael, Hicks Rodney J, Everitt Sarah
Peter MacCallum Cancer Institute.
J Thorac Oncol. 2006 Jan;1(1):81-4.
PET-CT is an exciting new imaging technology that simultaneously acquires detailed structural and functional imaging information. PET is having an increasing impact on the management of loco-regionally advanced non-small cell lung cancer with radiotherapy. PET combined with CT is much more accurate than CT alone in staging lung cancer and patients treated with radical radiotherapy or chemoradiotherapy have better outcomes because of superior patient selection. PET also has the potential to improve radiotherapy planning by minimizing unnecessary irradiation of normal tissues and by reducing the risk of geographic miss. PET influences treatment planning in a high proportion of cases and therefore radiotherapy dose escalation without PET may be futile.
正电子发射断层扫描-计算机断层扫描（PET-CT）是一项令人振奋的新型成像技术，它能同时获取详细的结构和功能成像信息。在局部晚期非小细胞肺癌的放射治疗管理中，正电子发射断层扫描（PET）的影响日益增大。在肺癌分期方面，PET与CT联合使用比单纯使用CT更为准确，并且接受根治性放疗或放化疗的患者由于患者选择更优，预后也更好。PET还有望通过尽量减少对正常组织的不必要照射以及降低靶区遗漏风险来改善放射治疗计划。在很大一部分病例中，PET会影响治疗计划，因此在没有PET的情况下提高放疗剂量可能毫无意义。
