一个显著的结局。
A marked end.
作者信息
Chen Xuemei
出版信息
Nat Struct Mol Biol. 2007 Apr;14(4):259-60. doi: 10.1038/nsmb0407-259.
Abstract
microRNAs (miRNAs) and small interfering RNAs from plants are 2′--methylated at their 3′ termini. Although miRNAs from animals are not methylated, two studies show that the recently identified mammalian Piwi-interacting RNAs carry a 2′--methyl group on the 3′ terminal ribose.
摘要
植物中的微小RNA（miRNA）和小干扰RNA在其3'末端发生2'-O-甲基化。虽然动物中的miRNA没有甲基化，但两项研究表明，最近发现的哺乳动物Piwi相互作用RNA在3'末端核糖上带有一个2'-O-甲基基团。
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本文引用的文献
1
Mouse Piwi-interacting RNAs are 2'-O-methylated at their 3' termini.小鼠Piwi相互作用RNA在其3'末端被2'-O-甲基化。
Nat Struct Mol Biol. 2007 Apr;14(4):347-8. doi: 10.1038/nsmb1218. Epub 2007 Mar 25.
2
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Nat Struct Mol Biol. 2007 Apr;14(4):349-50. doi: 10.1038/nsmb1220. Epub 2007 Mar 25.
3
A slicer-mediated mechanism for repeat-associated siRNA 5' end formation in Drosophila.果蝇中一种由切片酶介导的与重复序列相关的小干扰RNA 5'端形成机制。
Science. 2007 Mar 16;315(5818):1587-90. doi: 10.1126/science.1140494. Epub 2007 Feb 22.
4
Slicer and the argonautes.切片机与精氨酸酶
Nat Chem Biol. 2007 Jan;3(1):36-43. doi: 10.1038/nchembio848.
5
A distinct small RNA pathway silences selfish genetic elements in the germline.一条独特的小RNA通路可使种系中的自私遗传元件失活。
Science. 2006 Jul 21;313(5785):320-4. doi: 10.1126/science.1129333. Epub 2006 Jun 29.
6
Characterization of the piRNA complex from rat testes.大鼠睾丸中piRNA复合物的特征分析。
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