Chen Xuemei
Nat Struct Mol Biol. 2007 Apr;14(4):259-60. doi: 10.1038/nsmb0407-259.
microRNAs (miRNAs) and small interfering RNAs from plants are 2′--methylated at their 3′ termini. Although miRNAs from animals are not methylated, two studies show that the recently identified mammalian Piwi-interacting RNAs carry a 2′--methyl group on the 3′ terminal ribose.
植物中的微小RNA（miRNA）和小干扰RNA在其3'末端发生2'-O-甲基化。虽然动物中的miRNA没有甲基化，但两项研究表明，最近发现的哺乳动物Piwi相互作用RNA在3'末端核糖上带有一个2'-O-甲基基团。
