Local anaesthetic block of sodium channels: raising the barrier.
作者信息
Scheuer Todd
机构信息
Department of Pharmacology, Mailstop 357280, University of Washington, Seattle, WA 98195-7280, USA.
出版信息
J Physiol. 2007 Jun 1;581(Pt 2):423. doi: 10.1113/jphysiol.2007.133637. Epub 2007 Apr 5.
Abstract
摘要
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本文引用的文献
1
Charge at the lidocaine binding site residue Phe-1759 affects permeation in human cardiac voltage-gated sodium channels.
J Physiol. 2007 Jun 1;581(Pt 2):741-55. doi: 10.1113/jphysiol.2007.130161. Epub 2007 Mar 15.
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Molecular modeling of local anesthetic drug binding by voltage-gated sodium channels.
Mol Pharmacol. 2005 Dec;68(6):1611-22. doi: 10.1124/mol.105.014803. Epub 2005 Sep 20.
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Nature. 2004 Aug 12;430(7001):806-10. doi: 10.1038/nature02735.
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Molecular determinants of state-dependent block of Na+ channels by local anesthetics.
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