老年女性和男性的早发性白发、脱发及低骨矿物质密度：兰乔贝纳多研究
Premature graying, balding, and low bone mineral density in older women and men: the Rancho Bernardo study.
作者信息
Morton Deborah J, Kritz-Silverstein Donna, Riley Donna J, Barrett-Connor Elizabeth L, Wingard Deborah L
机构信息
Department of Family and Preventive Medicine, Division of Epidemiology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0622, USA.
出版信息
J Aging Health. 2007 Apr;19(2):275-85. doi: 10.1177/0898264307299274.
OBJECTIVE
The authors report the association of balding or graying with BMD in older adults.
METHOD
BMD was measured at the spine, hip, and total body in 1,207 participants. Of these, 508 women and 380 men responded to a 1986 survey about balding patterns; in 1994, all participants answered questions about graying.
RESULTS
Among men, 10.7% reported graying, and 51.1%, balding; 9.9% of women reported graying, and 9.5%, balding. Models were adjusted for age, body mass index, alcohol consumption, smoking, exercise, calcium supplements, diuretics, glucocorticoids, thyroid hormone, and estrogen.
CONCLUSION
Graying was not significantly associated with BMD in either group. Balding men averaged 5% lower total body BMD (p </= 0.05), and balding women had ~24% higher mean hip BMD (p </= 0.05). Graying and balding women reported a higher proportion of current estrogen use; balding women reported more use of glucocorticosteroids. Balding women using estrogen may explain the higher BMD.
目的
作者报告老年人中脱发或白发与骨密度（BMD）之间的关联。
方法
对1207名参与者进行了脊柱、髋部和全身的骨密度测量。其中，508名女性和380名男性回答了1986年关于脱发模式的调查；1994年，所有参与者回答了关于白发的问题。
结果
男性中，10.7%报告有白发，51.1%报告有脱发；女性中，9.9%报告有白发，9.5%报告有脱发。模型对年龄、体重指数、饮酒量、吸烟、运动、钙补充剂、利尿剂、糖皮质激素、甲状腺激素和雌激素进行了校正。
结论
两组中白发与骨密度均无显著关联。脱发男性的全身骨密度平均低5%（p≤0.05），脱发女性的平均髋部骨密度高约24%（p≤0.05）。白发和脱发女性报告当前使用雌激素的比例较高；脱发女性报告使用糖皮质激素的情况较多。使用雌激素的脱发女性可能解释了较高的骨密度。
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