Kools A M
Ramsey Clinic, St Paul, MN 55101.
Postgrad Med. 1992 Feb 15;91(3):109-14. doi: 10.1080/00325481.1992.11701228.
Five major types of viral hepatitis have been identified. Hepatitis A is an acute, usually self-limited illness. Prophylaxis with immune globulin (Gamastan, Gammar) is effective in household and sexual contacts of infected patients. Hepatitis B has both acute and chronic forms. Treatment trials for chronic hepatitis B with interferon alfa-2b have shown promise. Hepatitis C is the name now given to non-A non-B hepatitis. Interferon alfa-2b (Intron A) has been approved for treatment of chronic hepatitis C. Hepatitis D occurs only in patients with hepatitis B. The only treatment for hepatitis D is prevention of hepatitis B. Hepatitis E is seen after natural disasters in developing regions of the world. Further advances in serologic testing and treatment of viral hepatitis can be expected.
已确定有五种主要类型的病毒性肝炎。甲型肝炎是一种急性疾病，通常为自限性。对受感染患者的家庭接触者和性接触者使用免疫球蛋白（如伽马球蛋白、人免疫球蛋白）进行预防是有效的。乙型肝炎有急性和慢性两种形式。用α-2b干扰素治疗慢性乙型肝炎的试验已显示出前景。丙型肝炎是现在对非甲非乙型肝炎的命名。α-2b干扰素（英特龙A）已被批准用于治疗慢性丙型肝炎。丁型肝炎仅发生于乙型肝炎患者中。丁型肝炎的唯一治疗方法是预防乙型肝炎。戊型肝炎在世界发展中地区的自然灾害后可见。预计在病毒性肝炎的血清学检测和治疗方面会有进一步进展。
