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肿瘤坏死因子拮抗剂在一名类风湿关节炎合并HIV感染患者中的成功应用。

Successful etanercept use in an HIV-positive patient with rheumatoid arthritis.

作者信息

Kaur Primal P, Chan Virginia C, Berney Steven N

机构信息

Division of Rheumatology, Department of Medicine, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

出版信息

J Clin Rheumatol. 2007 Apr;13(2):79-80. doi: 10.1097/01.rhu.0000260411.75599.39.

DOI:10.1097/01.rhu.0000260411.75599.39
PMID:17414534
Abstract

Limited information exists on treatment of rheumatoid arthritis in a patient with coexisting human immunodeficiency virus (HIV) infection. We report a case of a patient with rheumatoid arthritis who then became HIV positive. His HIV viral load was controlled with antiretroviral therapy, but he continued to have active rheumatoid arthritis despite therapy with hydroxychloroquine, sulfasalazine, and corticosteroids. Because of unremitting rheumatoid disease, we are now treating him with a TNFalpha inhibitor, and his rheumatoid disease activity has decreased from 28 swollen and tender joint count to less than 5.

摘要

关于合并人类免疫缺陷病毒(HIV)感染的类风湿关节炎患者的治疗信息有限。我们报告了一例类风湿关节炎患者随后感染HIV的病例。他的HIV病毒载量通过抗逆转录病毒疗法得到控制,但尽管接受了羟氯喹、柳氮磺胺吡啶和皮质类固醇治疗,他仍患有活动性类风湿关节炎。由于类风湿疾病持续存在,我们现在用肿瘤坏死因子α抑制剂对他进行治疗,他的类风湿疾病活动度已从28个肿胀和压痛关节数降至不到5个。

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Septic shock after seasonal influenza vaccination in an HIV-infected patient during treatment with etanercept for rheumatoid arthritis: a case report.一名类风湿关节炎患者在使用依那西普治疗期间因季节性流感疫苗接种后发生感染性休克:病例报告
Clin Vaccine Immunol. 2013 May;20(5):761-4. doi: 10.1128/CVI.00081-13. Epub 2013 Mar 6.
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