Towle Vernon L, Hunter John D, Edgar J Christopher, Chkhenkeli Sozari A, Castelle Michael C, Frim David M, Kohrman Michael, Hecox Kurt E
Department of Neurology, The University of Chicago, Chicago, Illinois 60637, USA.
J Clin Neurophysiol. 2007 Apr;24(2):205-13. doi: 10.1097/WNP.0b013e318039b191.
It is possible to localize many aspects of cortical function and dysfunction without the use of direct electrical stimulation of cortex. This study explores the degree to which information can be obtained about functional cortical organization relative to epileptogenic regions through analysis of electrocorticographic recordings in the frequency domain. Information about the extent of seizure regions and the location of the normal sensory and motor homunculus and some higher language and memory related areas can be obtained through the analysis of task-related power spectrum changes and changes in lateral interelectrode coherence patterns calculated from interictal and ictal recordings.
不使用对皮质的直接电刺激来定位皮质功能和功能障碍的许多方面是可能的。本研究探讨了通过频域分析皮质电图记录，能够获取关于相对于致痫区域的功能性皮质组织信息的程度。通过分析任务相关的功率谱变化以及根据发作间期和发作期记录计算出的电极间横向相干模式的变化，可以获得关于癫痫发作区域范围、正常感觉和运动小人以及一些与语言和记忆相关的高级区域位置的信息。
