Zhou Hui, Hu Xiao-shu, Guo Zhi-rong, Shi Zu-min, Wu Ming, Zhang Jun, Sun Guo-xiang, Zhou Zheng-yuan, Yao Cai-liang
School of Radiological Medicine and Public Health, Soochow University, Suzhou 215123, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2006 Dec;27(12):1043-7.
To compare the significance of the application in Jiangsu population using the diagnostic criteria for metabolic syndrome(MS) proposed by the IDF in 2005, ATP III in 2005 and CDS in 2004.
Based on the populations in Jiangsu province from a project of Multiple Metabolic Disorders and MS, the study was conducted including 5888 cases, with data of plasma glucose, lipid profile, blood pressure, serum insulin etc. MS was diagnosed and compared according to these three definitions respectively.
The age-adjusted MS prevalence rates were 17.48%, 21.95% and 9.59% according to the IDF(2005), ATP III (2005) and CDS (2004) respectively. The agreement in the diagnosis of MS using ATP III (2005) and CDS(2004) definitions was 85.11%, and the agreement in the diagnosis of MS using IDF(2005) and CDS definitions was 87.35%. The agreement in the diagnosis of MS using IDF (2005) and ATP III (2005) definitions was 95.14%. The MS subjects diagnosed by the ATP III (2005) was 1.26 higher than subjects diagnosed by the IDF(2005) definition. The ratios of prevalence rates of high waist circumference(WC), MS_IDF (2005) and MS_ATP III (2005) was 2.17, 1.99 and 1.54 in sex ratio (woman to man).
The agreement in the diagnosis of MS using the IDF(2005) and ATP III (2005) definition was higher than using CDS(2004) and other two definitions. For diagnosing MS, the cut off of WC in IDF(2005) and ATP III (2005) seemed not appropriate and the diagnostic criteria used for ATP III (2005) (waist circumference of man 85 cm, woman 80 cm) could identify more MS.
比较国际糖尿病联盟（IDF）2005年提出的代谢综合征（MS）诊断标准、美国国家胆固醇教育计划成人治疗组第三次报告（ATP III）2005年版以及中国糖尿病学会（CDS）2004年版在江苏人群中的应用意义。
基于一项多代谢紊乱与MS项目中的江苏省人群开展研究，纳入5888例，收集其血糖、血脂、血压、血清胰岛素等数据。分别依据这三种定义对MS进行诊断并比较。
根据IDF（2005年）、ATP III（2005年）和CDS（2004年）标准，年龄调整后的MS患病率分别为17.48%、21.95%和9.59%。采用ATP III（2005年）和CDS（2004年）定义诊断MS的一致性为85.11%，采用IDF（2005年）和CDS定义诊断MS的一致性为87.35%。采用IDF（2005年）和ATP III（2005年）定义诊断MS的一致性为95.14%。ATP III（2005年）诊断出的MS患者比IDF（2005年）定义诊断出的患者多1.26倍。高腰围（WC）、MS_IDF（2005年）和MS_ATP III（2005年）患病率的性别比（女性与男性）分别为2.17、1.99和1.54。
采用IDF（2005年）和ATP III（2005年）定义诊断MS的一致性高于CDS（2004年）及其他两种定义。对于诊断MS而言，IDF（2005年）和ATP III（2005年）中WC的切点似乎不合适，ATP III（2005年）使用的诊断标准（男性腰围85厘米，女性腰围80厘米）能识别出更多的MS患者。
