Konstantinov B A, Dzemeshkevich S L, Rogov K A, Nenukov A K, Budaev V N, Palulina M V, Movsesov R V, Egorov T L, Kozlov A V, Burtsev P U
National Research Center of Surgery, Academy of Medical Sciences of the U.S.S.R., Moscow.
Artif Organs. 1991 Oct;15(5):363-8. doi: 10.1111/j.1525-1594.1991.tb00743.x.
The authors performed 12 acute (on dogs) and 12 chronic (on calves) assisted circulation experiments with the use of the total extracorporeal mechanical pump (TEMP) artificial ventricles. The functional morphological research of the myocardium suggests that in addition to the possibility of the biological heart function full replacement, the artificial ventricle also helps recover damages in both the myocardial infarction and distal zones. The critical time period up to the onset of artificial circulation is not more than 2 h, and after that myocardial changes are irreversible.
作者使用全体外机械泵（TEMP）人工心室进行了12次急性（在狗身上）和12次慢性（在小牛身上）辅助循环实验。心肌的功能形态学研究表明，除了完全替代生物心脏功能的可能性外，人工心室还有助于恢复心肌梗死区和远端区域的损伤。人工循环开始前的关键时间段不超过2小时，之后心肌变化是不可逆的。
