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原发性甲状旁腺功能亢进症中的甲状旁腺腺瘤:两例报告——主细胞腺瘤和嗜酸性细胞腺瘤

Parathyroid gland adenoma in primary hyperparathyroidism: report of two cases--chief and oxyphil cell adenoma.

作者信息

Yoshihara T, Morita M, Masuda T, Kanda T, Takemiya S

机构信息

Department of Otolaryngology, Tokyo Women's Medical College, Japan.

出版信息

Auris Nasus Larynx. 1991;18(2):189-97. doi: 10.1016/s0385-8146(12)80224-0.

DOI:10.1016/s0385-8146(12)80224-0
PMID:1741713
Abstract

Parathyroid adenomas are classified into two types: chief cell and oxyphil cell variants. In this report two types of parathyroid adenoma in association with hyperparathyroidism were examined. Both cases had suffered from renal calculi, and underwent operation. The laboratory tests showed high serum calcium and parathyroid hormone (PTH) levels. An exploratory surgery revealed a solitary tumor in each case. After extirpation of the parathyroid tumor these data returned to normal values. Electronmicroscopically, oxyphil cell adenoma in this report was characterized by numerous mitochondria and annulate lamellae in the cytoplasm. In some tumor cells secretory-like granules were observed.

摘要

甲状旁腺腺瘤分为两种类型

主细胞型和嗜酸细胞型。在本报告中,对两例伴有甲状旁腺功能亢进的甲状旁腺腺瘤进行了检查。两例患者均患有肾结石并接受了手术。实验室检查显示血清钙和甲状旁腺激素(PTH)水平升高。探查性手术显示每例均有一个孤立性肿瘤。切除甲状旁腺肿瘤后,这些数据恢复到正常水平。电镜下,本报告中的嗜酸细胞腺瘤的特征是细胞质内有大量线粒体和环状板层。在一些肿瘤细胞中观察到分泌样颗粒。

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