Rastogi Archana, Jain Manoj, Agarawal Tanu, Mishra Anand K, Gupta Sushil, Agarwal Amit
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.
Indian J Pathol Microbiol. 2006 Jul;49(3):404-6.
Parathyroid lipoadenoma is a rare variant of parathyroid adenoma showing intermingling of chief/ oxyphil cells with abundant mature adipose cells, the latter comprising 20-90% of the tumour. Approximately thirty-five cases have been reported previously. We report a case of 41-year old woman who presented with clinical manifestations of primary hyperparathyroidism. She had elevated serum calcium and parathyroid hormone levels. Radiological investigations suggested presence of adenoma. Intra-operatively, parathyroid adenoma was found in the neck in an ectopic location behind the carotid sheath and extending into the superior mediastinum. Clinicopathological findings of this rare tumour are discussed.
甲状旁腺脂肪瘤是甲状旁腺腺瘤的一种罕见变异型,表现为主细胞/嗜酸性细胞与大量成熟脂肪细胞混合存在,后者占肿瘤的20% - 90%。此前已报道约35例病例。我们报告一例41岁女性,她表现出原发性甲状旁腺功能亢进的临床表现。她的血清钙和甲状旁腺激素水平升高。影像学检查提示腺瘤存在。术中在颈部颈动脉鞘后方的异位位置发现甲状旁腺腺瘤,并延伸至上纵隔。本文讨论了这种罕见肿瘤的临床病理特征。