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甲状旁腺脂肪瘤:病例报告及文献复习

Parathyroid lipoadenoma: case report and review of the literature.

作者信息

Rastogi Archana, Jain Manoj, Agarawal Tanu, Mishra Anand K, Gupta Sushil, Agarwal Amit

机构信息

Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow.

出版信息

Indian J Pathol Microbiol. 2006 Jul;49(3):404-6.

Abstract

Parathyroid lipoadenoma is a rare variant of parathyroid adenoma showing intermingling of chief/ oxyphil cells with abundant mature adipose cells, the latter comprising 20-90% of the tumour. Approximately thirty-five cases have been reported previously. We report a case of 41-year old woman who presented with clinical manifestations of primary hyperparathyroidism. She had elevated serum calcium and parathyroid hormone levels. Radiological investigations suggested presence of adenoma. Intra-operatively, parathyroid adenoma was found in the neck in an ectopic location behind the carotid sheath and extending into the superior mediastinum. Clinicopathological findings of this rare tumour are discussed.

摘要

甲状旁腺脂肪瘤是甲状旁腺腺瘤的一种罕见变异型,表现为主细胞/嗜酸性细胞与大量成熟脂肪细胞混合存在,后者占肿瘤的20% - 90%。此前已报道约35例病例。我们报告一例41岁女性,她表现出原发性甲状旁腺功能亢进的临床表现。她的血清钙和甲状旁腺激素水平升高。影像学检查提示腺瘤存在。术中在颈部颈动脉鞘后方的异位位置发现甲状旁腺腺瘤,并延伸至上纵隔。本文讨论了这种罕见肿瘤的临床病理特征。

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