Carruez A J, González G D, Cabrerizo E L, Jabari S N, Echeverría R U, Renedo C F, Manchado O O
Rev Iber Endocrinol. 1975 Nov-Dec;22(132):505-16.
The authors studied the effects of intramuscular and intravenous administration of ACTH on plasma glucose and insulin in rabbits. They found well marked differences --specially in insulin behavior-- between the effects of ACTH in rabbits and in humans. In rabbits, the investigators observed hyperinsulinism unable to decrease glycemia levels. These data are discussed.
作者研究了肌肉注射和静脉注射促肾上腺皮质激素(ACTH)对兔血浆葡萄糖和胰岛素的影响。他们发现,ACTH对兔和对人的影响之间存在显著差异——尤其是在胰岛素反应方面。在兔中,研究人员观察到高胰岛素血症,但血糖水平并未降低。对这些数据进行了讨论。