脑池内注射促肾上腺皮质激素对犬血糖及肝糖原的影响
Effect of intracisternal injection of ACTH on blood glucose and hepatic glycogen in dogs.
作者信息
Agarwala G C
出版信息
Indian J Physiol Pharmacol. 1979 Oct-Dec;23(4):297-304.
The intracisternal administration of ACTH in a dose of 0.2 muU in mongrel dogs produced a significant (P less than 0.001) rise in blood glucose (BGL) and a fall (P less than 0.01) in hepatic glycogen concentration (HGC): in contrast its intravenous administration was devoid of this action. These changes were markedly reduced in the hepatic denervated animals and were completely abolished in animals with spinal cord transectomy. The above changes suggest that ACTH on the intracisternal administration causes a rise in the BGL by an action on the liver through the sympathetic fibers.
在杂种狗中，脑池内注射剂量为0.2微单位的促肾上腺皮质激素（ACTH）会导致血糖（BGL）显著升高（P<0.001），肝糖原浓度（HGC）降低（P<0.01）；相比之下，静脉注射则无此作用。在去神经支配的肝脏动物中，这些变化明显减少，而在脊髓横断的动物中则完全消失。上述变化表明，脑池内注射ACTH通过交感神经纤维作用于肝脏，从而导致BGL升高。
Zotero 插件