Poeniţă L, Claiciu I, Bărbulescu R, Plopeanu D
Rev Ig Bacteriol Virusol Parazitol Epidemiol Pneumoftiziol Pneumoftiziol. 1975 Oct-Dec;24(4):221-6.
A number of 1928 children were vaccinated intradermally with 12 series of BCG vaccine produced by the Cantacuzino Institute and 2 experimental vaccines, prepared in the same laboratory by the same current technique, i.e. a Romanian strain and a French strain, lot 1173 P2. With the experimental vaccines 2 doses were used, with the other vaccines a single standard dose of 0.10 mg. Appraisal of tuberculin sensitivity 8-10 weeks after vaccination showed differences in tuberculin duration, varying between 13.23 mm and 16.27 mm in diameter with the selected vaccines (using 2 units PPD) and were much smaller (8.6 mm -- 12.28 mm) with the operational series of vaccines.
1928名儿童接受了坎塔库齐诺研究所生产的12批卡介苗以及两种实验性疫苗的皮内接种。这两种实验性疫苗由同一实验室采用相同的现行技术制备,即一株罗马尼亚菌株和一株法国菌株(批号1173 P2)。实验性疫苗使用两剂,其他疫苗使用0.10毫克的单一标准剂量。接种疫苗8 - 10周后对结核菌素敏感性的评估显示,所选疫苗(使用2单位PPD)的结核菌素硬结直径在13.23毫米至16.27毫米之间,而实际使用的疫苗批次硬结直径要小得多(8.6毫米 - 12.28毫米)。