Fan Zhi-Min, Song Dong, Wang Lei, Fu Tong, Yang Ming, Liu Gou-Jin
Bethune-Laval Oncology Unit, First Hospital, Jilin University, Changchun 130021, China.
Zhonghua Yi Xue Za Zhi. 2007 Jan 9;87(2):93-5.
To study the feasibility of total mastectomy and axillary dissection with conservation of the nipple-areola complex, and immediate reconstruction with artificial prosthesis in the treatment of early breast cancer.
The 20 patients with breast cancer (TNM stage I, 6 patients; stage II, 14 patients) underwent the total mastectomy axillary dissection with conservation of the nipple-areola complex, and immediate reconstruction with artificial prosthesis. Post-operation they were given chemotherapy, radiotherapy, endocrine therapy.
The mean follow-up for the entire group of 20 patients was 52.3 months, eighteen patients were more than 36 months. All patients were still alive, without local or regional recurrences. One patient suffered from multiple metastasis of liver and bone nine months after the operation, who has living five years now.
Total mastectomy and axillary dissection with conservation of the nipple-areola complex, and immediate reconstruction with artificial prosthesis on selected patients with breast cancer is an oncologically acceptable procedure with superior cosmetic results, without increasing the risk of local recurrences, complications and influencing the effects of postoperative adjuvant treatment.
探讨保留乳头乳晕复合体的全乳切除加腋窝淋巴结清扫及即刻人工假体乳房重建术治疗早期乳腺癌的可行性。
20例乳腺癌患者（TNM分期Ⅰ期6例，Ⅱ期14例）行保留乳头乳晕复合体的全乳切除加腋窝淋巴结清扫及即刻人工假体乳房重建术。术后给予化疗、放疗、内分泌治疗。
20例患者平均随访52.3个月，18例超过36个月。所有患者均存活，无局部或区域复发。1例患者术后9个月发生肝、骨多发转移，现存活5年。
对选择合适的乳腺癌患者行保留乳头乳晕复合体的全乳切除加腋窝淋巴结清扫及即刻人工假体乳房重建术，在肿瘤学上是可接受的，美容效果良好，不增加局部复发风险及并发症，不影响术后辅助治疗效果。
