• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

髋臼唇的关节镜修复:绵羊模型愈合情况的组织学评估

Arthroscopic repair of the acetabular labrum: a histologic assessment of healing in an ovine model.

作者信息

Philippon Marc J, Arnoczky Steven P, Torrie Alec

机构信息

Steadman Hawkins Clinic, Vail, Colorado, USA.

出版信息

Arthroscopy. 2007 Apr;23(4):376-80. doi: 10.1016/j.arthro.2007.01.017.

DOI:10.1016/j.arthro.2007.01.017
PMID:17418329
Abstract

PURPOSE

Recently, arthroscopic repair has been advocated for the treatment of labral tears. The purpose of this study was to document the histologic healing process in an arthroscopically repaired acetabular-labral detachment in an ovine model.

METHODS

A total of 10 skeletally mature female sheep underwent unilateral arthroscopic labral repair. A 1.5-cm-long incision was made at the junction of the labrum and acetabulum. The labral detachment was then repaired arthroscopically with a single suture anchor. Postoperatively, the animals were confined to small indoor pens, and no form of immobilization was used. After 12 weeks, the animals were killed and the labral repair evaluated via routine histology. Normal labra from 3 nonoperative animals were also processed for histology.

RESULTS

The acetabular labrum of the sheep is an avascular, fibrocartilaginous structure similar in anatomic design to that of human beings. All arthroscopically repaired labra appeared stable and grossly healed at 12 weeks. Histologically, labral healing appeared to occur via fibrovascular scar tissue originating from the joint capsule or the exposed bony attachment of the labrum (or both). However, the labral healing was incomplete in all specimens, with a shallow, superficial cleft remaining at the junction of the labrum and the articular surface of the acetabulum.

CONCLUSIONS

Arthroscopically repaired acetabular-labral lesions in sheep are capable of healing via fibrovascular repair tissue or direct reattachment via new bone formation (or both).

CLINICAL RELEVANCE

The ability of labral detachments to heal in this animal model provides the rationale for additional investigations into the clinical efficacy of arthroscopic labral repair in human beings.

摘要

目的

近来,关节镜下修复术被提倡用于治疗盂唇撕裂。本研究的目的是记录在羊模型中关节镜下修复髋臼盂唇分离后的组织学愈合过程。

方法

总共10只骨骼成熟的雌性绵羊接受了单侧关节镜下盂唇修复术。在盂唇与髋臼的交界处做一个1.5厘米长的切口。然后通过单个缝线锚钉在关节镜下修复盂唇分离。术后,动物被限制在室内小围栏中,未采用任何形式的固定。12周后,处死动物并通过常规组织学评估盂唇修复情况。还对3只未手术动物的正常盂唇进行了组织学处理。

结果

绵羊的髋臼盂唇是一种无血管的纤维软骨结构,其解剖设计与人类相似。所有关节镜下修复的盂唇在12周时均显得稳定且大体愈合。组织学上,盂唇愈合似乎是通过源自关节囊或盂唇暴露的骨附着处(或两者)的纤维血管瘢痕组织实现的。然而,所有标本中的盂唇愈合均不完全,在盂唇与髋臼关节面的交界处仍残留一个浅而表浅的裂隙。

结论

绵羊关节镜下修复的髋臼盂唇损伤能够通过纤维血管修复组织或通过新骨形成直接重新附着(或两者)实现愈合。

临床意义

盂唇分离在该动物模型中的愈合能力为进一步研究关节镜下盂唇修复术在人类中的临床疗效提供了理论依据。

相似文献

1
Arthroscopic repair of the acetabular labrum: a histologic assessment of healing in an ovine model.髋臼唇的关节镜修复:绵羊模型愈合情况的组织学评估
Arthroscopy. 2007 Apr;23(4):376-80. doi: 10.1016/j.arthro.2007.01.017.
2
Histologic assessment of acetabular labrum healing.髋臼唇愈合的组织学评估。
Arthroscopy. 2012 Dec;28(12):1784-9. doi: 10.1016/j.arthro.2012.06.012. Epub 2012 Oct 17.
3
Labral base refixation in the hip: rationale and technique for an anatomic approach to labral repair.髋关节盂唇基底部修复固定术:盂唇修复的解剖学入路的原理和技术。
Arthroscopy. 2010 Sep;26(9 Suppl):S81-9. doi: 10.1016/j.arthro.2010.01.021. Epub 2010 Jul 7.
4
Effect of acetabular labral tears, repair and resection on hip cartilage strain: A 7T MR study.髋臼唇撕裂、修复和切除对髋关节软骨应变的影响:7T MRI 研究。
J Biomech. 2010 Mar 22;43(5):858-63. doi: 10.1016/j.jbiomech.2009.11.016. Epub 2009 Dec 16.
5
Arthroscopic acetabular recession with chondrolabral preservation.保留软骨盂唇的关节镜下髋臼凹陷术。
Am J Orthop (Belle Mead NJ). 2013 Apr;42(4):181-4.
6
Management of labral tears of the hip in young patients.年轻患者髋关节盂唇撕裂的管理
Orthop Clin North Am. 2013 Oct;44(4):477-87. doi: 10.1016/j.ocl.2013.06.003. Epub 2013 Jul 25.
7
Arthroscopic treatment for acetabular labral tears of the hip without bony dysmorphism.髋关节髋臼唇撕裂的关节镜治疗,不伴骨畸形。
Am J Sports Med. 2011 Jul;39 Suppl:79S-84S. doi: 10.1177/0363546511412915.
8
Structure and vascularization of the acetabular labrum with regard to the pathogenesis and healing of labral lesions.髋臼唇的结构与血管分布及其与唇缘病变的发病机制和愈合的关系。
Arch Orthop Trauma Surg. 2003 Jul;123(6):283-8. doi: 10.1007/s00402-003-0527-7. Epub 2003 Jun 7.
9
Magnetic resonance imaging of the hip: detection of labral and chondral abnormalities using noncontrast imaging.髋关节的磁共振成像:使用非增强成像检测盂唇和软骨异常
Arthroscopy. 2005 Apr;21(4):385-93. doi: 10.1016/j.arthro.2004.12.011.
10
Repair of the adult acetabular labrum.成人髋臼盂唇修复术。
Arthroscopy. 2006 May;22(5):567.e1-3. doi: 10.1016/j.arthro.2005.07.033.

引用本文的文献

1
Global Acetabular Retroversion Is Associated With an Increased Risk of Conversion to Total Hip Arthroplasty After Primary Hip Arthroscopic Surgery: A Propensity Score-Matched Analysis With a Minimum 8-Year Follow-up.全球髋臼后倾与初次髋关节镜手术后转为全髋关节置换术的风险增加相关:一项倾向评分匹配分析,随访至少8年。
Orthop J Sports Med. 2025 Jun 17;13(6):23259671251343840. doi: 10.1177/23259671251343840. eCollection 2025 Jun.
2
Association Between Chondrolabral Junction Breakdown and Conversion to Total Hip Arthroplasty After Hip Arthroscopy for Symptomatic Labral Tears: Minimum 8-Year Follow-up.髋关节镜治疗症状性盂唇撕裂后盂唇关节连接破裂与全髋关节置换术的转换:至少 8 年随访。
Am J Sports Med. 2024 Apr;52(5):1153-1164. doi: 10.1177/03635465241234258. Epub 2024 Mar 12.
3
Fixation strength in arthroscopic labral repair of the hip: A head-to-head comparison of the biomechanical performance of a biocompatible vs. all-suture anchor in the setting of acetabuloplasty.髋关节镜下盂唇修复中的固定强度:髋臼成形术中生物相容型与全缝线锚钉生物力学性能的头对头比较。
PLoS One. 2023 Nov 2;18(11):e0293738. doi: 10.1371/journal.pone.0293738. eCollection 2023.
4
Labral Reconstruction via Capsular Augmentation Maintains Perfusion to the Acetabular Labrum and Locally Transferred Autograft: An in Vivo Laser Doppler Flowmetry Analysis.通过关节囊增强进行盂唇重建可维持髋臼盂唇及局部转移自体移植物的灌注:一项体内激光多普勒血流仪分析
JB JS Open Access. 2023 Sep 26;8(3). doi: 10.2106/JBJS.OA.23.00026. eCollection 2023 Jul-Sep.
5
Prehabilitation and Rehabilitation Program for Patients Undergoing Arthroscopic Acetabular Labral Repair: Response.接受关节镜下髋臼盂唇修复术患者的术前康复和康复计划:回应
Orthop J Sports Med. 2022 Aug 31;10(8):23259671221119820. doi: 10.1177/23259671221119820. eCollection 2022 Aug.
6
Prehabilitation and Rehabilitation Program for Patients Undergoing Arthroscopic Acetabular Labral Repair: A Comprehensive 5-Phase Patient-Guided Program.关节镜下髋臼盂唇修复患者的术前康复和康复计划:一项全面的五阶段患者指导计划。
Orthop J Sports Med. 2022 Feb 8;10(2):23259671211071073. doi: 10.1177/23259671211071073. eCollection 2022 Feb.
7
Comparison Between Hip Arthroscopic Surgery and Periacetabular Osteotomy for the Treatment of Patients With Borderline Developmental Dysplasia of the Hip: A Systematic Review.髋关节镜手术与髋臼周围截骨术治疗髋关节边缘性发育不良患者的比较:一项系统评价
Orthop J Sports Med. 2021 May 4;9(5):23259671211007401. doi: 10.1177/23259671211007401. eCollection 2021 May.
8
Allocation of Anchors During Labral Repair: A Multicenter Cohort Analysis of Labral Treatment in Hip Arthroscopy.髋臼唇修复术中锚钉的植入:髋关节镜下髋臼唇治疗的多中心队列分析
Orthop J Sports Med. 2021 Feb 18;9(2):2325967120981983. doi: 10.1177/2325967120981983. eCollection 2021 Feb.
9
[Research progress in arthroscopic treatment of acetabular labrum injury].[髋臼盂唇损伤的关节镜治疗研究进展]
Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2020 Dec 15;34(12):1607-1611. doi: 10.7507/1002-1892.202002161.
10
Expression profile of matrix metalloproteinases in the labrum of femoroacetabular impingement.股骨髋臼撞击症盂唇中基质金属蛋白酶的表达谱
Bone Joint Res. 2020 May 16;9(4):173-181. doi: 10.1302/2046-3758.94.BJR-2019-0083.R1. eCollection 2020 Apr.