Meijer G J, Mel P, Koole R, Cune M S
Department of Oral & Maxillofacial Surgery, Prosthodontics and Special Dental Care, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, the Netherlands.
Int J Oral Maxillofac Surg. 2007 Jul;36(7):646-8. doi: 10.1016/j.ijom.2007.02.002. Epub 2007 Apr 5.
Surgical treatment of malignancies involving the oral cavity often results in an altered anatomical situation, which may severely hamper oral function. Postoperative radiotherapy resulting in reduced salivary secretion further worsens functions such as speech, chewing (mastication) and swallowing. In order to improve oral functioning, the use of dental implants was proposed. To reconstruct the edentulous mandible, especially in cases involving postoperative irradiation, implant-borne prosthetic construction on four permucosal implants has been advocated, but this treatment concept has some practical drawbacks. As the chewing force is reduced as a result of irradiation of the masticatory muscles, it is hypothesized that a fixed prosthetic construction on only two implants is a feasible alternative. Up until now 10 patients have been treated successfully according to this concept at the authors' clinic.
涉及口腔的恶性肿瘤的手术治疗常常会导致解剖结构改变，这可能严重妨碍口腔功能。术后放疗导致唾液分泌减少，进一步恶化诸如言语、咀嚼（咀嚼功能）和吞咽等功能。为了改善口腔功能，有人提出使用牙种植体。为了重建无牙下颌骨，特别是在涉及术后放疗的病例中，有人主张在四个黏膜下种植体上进行种植体支持的修复体构建，但这种治疗理念存在一些实际缺陷。由于咀嚼肌放疗导致咀嚼力下降，据推测仅在两个种植体上进行固定修复体构建是一种可行的替代方案。到目前为止，作者所在诊所已根据这一理念成功治疗了10例患者。
