Jakubec P, Kolek V, Procházka V, Konecný M, Jakubcová T
Klinika plicních nemocí a tuberkulózy Lékarské fakulty UP a FN Olomouc.
Vnitr Lek. 2007 Feb;53(2):135-42.
Pancreatic diseases are often accompanied by pleuropulmonal complications. Acute pancreatitis may induce a number of various pathological findings in respiratory tract including hypoxemia, decrease of transfer-factor (DLCO), decrease of transfer-coefficient (DLCO/VO), decrease in forced expiratory flow 25%- 75% of forced vital capacity (FEF25-75%), elevated and/or immobile diaphragm, basal atelectasis, unilateral or bilateral pulmonary infiltrations, mediastinal pseudocyst and pleural effusion. Acute respiratory distress syndrome (ARDS) is the most dangerous complication of acute pancreatitis. Large, recurrent pleural effusion is sometimes present in chronic pancreatitis, typically with a very high concentration of amylase in pleural fluid. Pancreaticopleural fistula (PPF) is the most common cause of this type of pleural effusion. We describe a study group of 3 patients with PPF and pleural effusion, their clinical symptoms, diagnostics and management.
胰腺疾病常伴有胸膜肺部并发症。急性胰腺炎可能在呼吸道引发多种病理表现,包括低氧血症、转运因子(DLCO)降低、转运系数(DLCO/VO)降低、用力肺活量25%-75%时的用力呼气流量(FEF25-75%)降低、膈肌抬高和/或活动受限、基底肺不张、单侧或双侧肺部浸润、纵隔假性囊肿和胸腔积液。急性呼吸窘迫综合征(ARDS)是急性胰腺炎最危险的并发症。慢性胰腺炎有时会出现大量反复胸腔积液,典型表现为胸腔积液中淀粉酶浓度极高。胰胸膜瘘(PPF)是这类胸腔积液最常见的原因。我们描述了一组3例患有PPF和胸腔积液的患者,包括他们的临床症状、诊断和治疗。