Min Byung Wook, Urn Jun Won, Moon Hong Young
Department of Surgery, Korea University College of Medicine, Seoul, Korea.
Hepatogastroenterology. 2007 Jan-Feb;54(73):63-6.
BACKGROUND/AIMS: This investigation aimed to estimate the value of regular follow-up programs after curative resection for colorectal cancer.
We compared the recurrence rate, rate of curative re-resection, and survival rate between groups who had either regular or irregular follow-up. The medical records of 397 consecutive patients, who underwent a curative resection for colorectal cancer between January 1994 and December 1997, were analyzed retrospectively.
The recurrence rate was 19.4% and 20.8% in the regular and irregular follow-up groups (P > 0.05), respectively. There was a significant difference in the asymptomatic recurrence rate (62.9 vs. 18.7%; P = 0.021), but curative re-resection was possible in 18 (29.0%) of those patients with cancer recurrence in the regular follow-up group, and in 2 (12.5%) in the irregular follow-up group, which was not significantly different (P > 0.05). 5-year survival rate between the groups was not significantly different (78.1 vs. 61.2%; P > 0.05).
A regular follow-up program after a curative resection for colorectal cancer, although facilitating detection of recurrence before symptoms developed, was unlikely to succeed in increasing the rate of a curative intent re-resection and survival remarkably.
背景/目的:本研究旨在评估结直肠癌根治性切除术后定期随访计划的价值。
我们比较了接受定期或不定期随访的两组患者之间的复发率、根治性再次切除率和生存率。对1994年1月至1997年12月期间连续397例行结直肠癌根治性切除患者的病历进行回顾性分析。
定期随访组和不定期随访组的复发率分别为19.4%和20.8%(P>0.05)。无症状复发率存在显著差异(62.9%对18.7%;P=0.021),但定期随访组中18例(29.0%)癌症复发患者可行根治性再次切除,不定期随访组为2例(12.5%),差异无统计学意义(P>0.05)。两组间5年生存率差异无统计学意义(78.1%对61.2%;P>0.05)。
结直肠癌根治性切除术后的定期随访计划,虽然有助于在症状出现前发现复发,但不太可能显著提高根治性再次切除率和生存率。