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结直肠癌根治性手术后定期随访的作用。

Role of regular follow-up after curative surgery for colorectal cancer.

作者信息

Min Byung Wook, Urn Jun Won, Moon Hong Young

机构信息

Department of Surgery, Korea University College of Medicine, Seoul, Korea.

出版信息

Hepatogastroenterology. 2007 Jan-Feb;54(73):63-6.

Abstract

BACKGROUND/AIMS: This investigation aimed to estimate the value of regular follow-up programs after curative resection for colorectal cancer.

METHODOLOGY

We compared the recurrence rate, rate of curative re-resection, and survival rate between groups who had either regular or irregular follow-up. The medical records of 397 consecutive patients, who underwent a curative resection for colorectal cancer between January 1994 and December 1997, were analyzed retrospectively.

RESULTS

The recurrence rate was 19.4% and 20.8% in the regular and irregular follow-up groups (P > 0.05), respectively. There was a significant difference in the asymptomatic recurrence rate (62.9 vs. 18.7%; P = 0.021), but curative re-resection was possible in 18 (29.0%) of those patients with cancer recurrence in the regular follow-up group, and in 2 (12.5%) in the irregular follow-up group, which was not significantly different (P > 0.05). 5-year survival rate between the groups was not significantly different (78.1 vs. 61.2%; P > 0.05).

CONCLUSIONS

A regular follow-up program after a curative resection for colorectal cancer, although facilitating detection of recurrence before symptoms developed, was unlikely to succeed in increasing the rate of a curative intent re-resection and survival remarkably.

摘要

背景/目的:本研究旨在评估结直肠癌根治性切除术后定期随访计划的价值。

方法

我们比较了接受定期或不定期随访的两组患者之间的复发率、根治性再次切除率和生存率。对1994年1月至1997年12月期间连续397例行结直肠癌根治性切除患者的病历进行回顾性分析。

结果

定期随访组和不定期随访组的复发率分别为19.4%和20.8%(P>0.05)。无症状复发率存在显著差异(62.9%对18.7%;P=0.021),但定期随访组中18例(29.0%)癌症复发患者可行根治性再次切除,不定期随访组为2例(12.5%),差异无统计学意义(P>0.05)。两组间5年生存率差异无统计学意义(78.1%对61.2%;P>0.05)。

结论

结直肠癌根治性切除术后的定期随访计划,虽然有助于在症状出现前发现复发,但不太可能显著提高根治性再次切除率和生存率。

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