Di Matteo J, Vacheron A, Bouramoue C, Audoin J, Gilles R
Sem Hop. 1975 Mar 14;51(13):843-54.
The authors report a clinical and phonocardiographic study of functional aortic systolic murmurs in 26 elderly patients, in 19 of which the lesion was confirmed pathologically. Systolic murmurs radiating across the chest in elderly have the same clinical characteristics as aortic stenosis from which they may, however, be distinguished owing to the: absence of a thrill during systole. The brief duration and the proto-meso-systolic position of the murmur with early inscription of maximal oscillations on the phonocardiogram. Conversion of the second aortic sound. Almost constant absence of a diastolic murmur. Normal carotid arteriogram, including normal ejection time after correction and time of half rise. "Innocent" systolic murmurs are due to calcification of the aortic valve without stenosis, and/or dilatation of the ascending aorta. There is no systolic pressure gradient between the left ventricle and the aorta during cardiac catheterisation. No lesions were found in the mitral valve suggesting mitral incompetence, therefore, we consider the term mitro-aortic murmur used by Huchard should be dropped; Radiation of the murmur from the apex of the heart up into the neck may be explained by the simultaneous occurrence of anatomical changes due to age and/or hypertension and by the vibratory nature of the murmurs which become propagated above and below their origin, as shown by the intracardiac recordings.
作者报告了对26例老年患者功能性主动脉收缩期杂音的临床和心音图研究,其中19例病变经病理证实。老年患者中向胸部广泛传导的收缩期杂音具有与主动脉瓣狭窄相同的临床特征,然而,由于以下几点可将它们区分开来:收缩期无震颤;杂音持续时间短,呈早-中收缩期,心音图上最大振动出现早;第二心音改变;几乎始终无舒张期杂音;颈动脉造影正常,包括校正后射血时间和上升时间正常。“无害的”收缩期杂音是由于主动脉瓣钙化但无狭窄和/或升主动脉扩张所致。心导管检查时左心室与主动脉之间无收缩期压力阶差。二尖瓣未发现提示二尖瓣关闭不全的病变,因此,我们认为Huchard使用的“二尖瓣-主动脉杂音”这一术语应摒弃;杂音从心尖向上传至颈部可解释为年龄和/或高血压导致的解剖学改变同时出现,以及杂音的振动性质使其在起源部位上下传播,心内记录已证实这一点。