Choi Soo-Jung, Song Jae Seok, Kim Chunghwan, Shin Myung Jin, Ryu Dae Sik, Ahn Jae Hong, Jung Seung Moon, Park Man Soo
Department of Radiology, GangNeung Asan Hospital, University of Ulsan College of Medicine, GangNeung, Korea.
Korean J Radiol. 2007 Mar-Apr;8(2):156-63. doi: 10.3348/kjr.2007.8.2.156.
We wanted to investigate the relationship between the magnetic resonance (MR) findings and the clinical outcome after treatment with non-surgical transforaminal epidural steroid injections (ESI) for lumbar herniated intervertebral disc (HIVD) patients.
Transforaminal ESI were performed in 91 patients (50 males and 41 females, age range: 13-78 yrs) because of lumbosacral HIVD from March 2001 to August 2002. Sixty eight patients whose MRIs and clinical follow-ups were available were included in this study. The medical charts were retrospectively reviewed and the patients were divided into two groups; the successful (responders, n = 41) and unsatisfactory (non-responders, n = 27) outcome groups. A successful outcome required a patient satisfaction score greater than two and a pain reduction score greater than 50%. The MR findings were retrospectively analyzed and compared between the two groups with regard to the type (protrusion, extrusion or sequestration), hydration (the T2 signal intensity), location (central, right/left central, subarticular, foraminal or extraforaminal), and size (volume) of the HIVD, the grade of nerve root compression (grade 1 abutment, 2 displacement and 3 entrapment), and an association with spinal stenosis.
There was no significant difference between the responders and non-responders in terms of the type, hydration and size of the HIVD, or an association with spinal stenosis (p > 0.05). However, the location of the HIVD and the grade of nerve root compression were different between the two groups (p < 0.05).
MRI could play an important role in predicting the clinical outcome of non-surgical transforaminal ESI treatment for patients with lumbar HIVD.
我们想要研究腰椎间盘突出症(HIVD)患者经皮椎间孔硬膜外类固醇注射(ESI)治疗后磁共振成像(MR)表现与临床疗效之间的关系。
2001年3月至2002年8月,对91例因腰骶部HIVD行椎间孔ESI治疗的患者(50例男性,41例女性,年龄范围:13 - 78岁)进行研究。本研究纳入了68例有MRI检查及临床随访资料的患者。对病历进行回顾性分析,并将患者分为两组:治疗成功组(反应者,n = 41)和治疗效果不满意组(无反应者,n = 27)。治疗成功的标准为患者满意度评分大于2分且疼痛减轻评分大于50%。对两组患者的MR表现进行回顾性分析和比较,包括HIVD的类型(突出型、脱出型或游离型)、含水量(T2信号强度)、位置(中央型、右/左中央型、关节突下型、椎间孔型或椎间孔外型)、大小(体积)、神经根受压程度(1级:毗邻,2级:移位,3级:卡压)以及与腰椎管狭窄的相关性。
在HIVD的类型、含水量和大小或与腰椎管狭窄的相关性方面,反应者与无反应者之间无显著差异(p > 0.05)。然而,两组之间HIVD的位置和神经根受压程度不同(p < 0.05)。
MRI在预测腰椎HIVD患者经皮椎间孔ESI非手术治疗的临床疗效方面可发挥重要作用。