Burgio G R, Notarangelo L D, Duse M, Ugazio A G
Department of Pediatrics, University of Pavia, Italy.
Pediatr Hematol Oncol. 1991 Jul-Sep;8(3):203-14. doi: 10.3109/08880019109033453.
Pediatric immunology is a recent and important branch of pediatrics. Besides development of vaccines, the discovery of primary immunodeficiencies has represented a major contribution in the history of pediatric immunology. Characterization of these disorders as inborn errors of immunity has been crucial for understanding the functional organization and ontogeny of the immune system. Thus, progress in the study of immunodeficiency diseases has contributed to progress in pediatric immunology as a whole. As a result of these advances and a major biotechnology breakthrough, new therapeutic strategies have been devised. The benefits of these strategies extend far beyond the area of immunodeficiencies; they permit better care of infants and give new therapeutic approaches to other inherited disorders.
儿科免疫学是儿科学中一个新兴且重要的分支。除了疫苗的研发，原发性免疫缺陷的发现是儿科免疫学史中的一项重大贡献。将这些疾病表征为先天性免疫缺陷对于理解免疫系统的功能组织和个体发育至关重要。因此，免疫缺陷疾病的研究进展推动了整个儿科免疫学的发展。由于这些进展以及一项重大的生物技术突破，人们设计出了新的治疗策略。这些策略的益处远远超出了免疫缺陷领域；它们有助于更好地照料婴儿，并为其他遗传性疾病提供了新的治疗方法。
