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罗伯特·科赫:结核杆菌发现一百周年,1882年。

Robert koch: centenary of the discovery of the tubercle bacillus, 1882.

作者信息

Sakula A

出版信息

Can Vet J. 1983 Apr;24(4):127-31.

Abstract

This is an account of the life and work of Robert Koch (1843-1910), Nobel Laureate in Medicine and a founder of the science of bacteriology. In particular, Koch's researches into tuberculosis are described - the discovery of the tubercle bacillus, the controversy regarding the human and bovine types, the Koch phenomenon, and the introduction of tuberculin, which proved to be ineffective as a cure but became important as a diagnostic tool in the management of tuberculosis. By his achievements in this field, Koch may be considered to be the father of the scientific study of tuberculosis. On the occasion of the centenary of Koch's discovery of the tubercle bacillus in 1882, we pay tribute to this great German master of medicine.Robert Koch's discovery of the tubercle bacillus in 1882 was a major event in the history of medicine, a turning point in our understanding and conquest of that deadly disease which had plagued mankind for millenia. After centuries of speculation as to the possible infectious nature of tuberculosis, Koch proved conclusively that the cause of the disease was infection by a specific micro-organism which he isolated. In tuberculosis, both seed and soil play their part, but without the seed - the tubercle bacillus - there is no disease.On the occasion of the centenary of Koch's discovery of the tubercle bacillus, we pay tribute to the father of the modern scientific approach to the management of tuberculosis.

摘要

本文讲述了医学诺贝尔奖得主、细菌学学科奠基人罗伯特·科赫(1843 - 1910)的生平与工作。特别描述了科赫对结核病的研究——结核杆菌的发现、关于人型和牛型结核杆菌的争论、科赫现象以及结核菌素的引入,事实证明结核菌素作为一种治疗方法并无效果,但在结核病管理中作为一种诊断工具却变得很重要。凭借在这一领域的成就,科赫可被视为结核病科学研究之父。在1882年科赫发现结核杆菌一百周年之际,我们向这位伟大的德国医学大师致敬。1882年罗伯特·科赫发现结核杆菌是医学史上的一件大事,是我们对困扰人类数千年的致命疾病的认识与征服过程中的一个转折点。经过几个世纪对结核病可能具有传染性的猜测,科赫确凿地证明了该病的病因是由他分离出的一种特定微生物感染所致。在结核病中,种子和土壤都起到了作用,但没有种子——结核杆菌——就不会有疾病。在科赫发现结核杆菌一百周年之际,我们向现代结核病管理科学方法之父致敬。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f57/1790283/ce3c15a8b497/canvetj00269-0054-a.jpg

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