接种疫苗的犬只体内的狂犬病抗体滴度。
Rabies antibody titres in vaccinated dogs.
作者信息
Derbyshire J B, Mathews K A
出版信息
Can Vet J. 1984 Oct;25(10):383-5.
In a field study, rabies virus neutralizing antibody titres were determined by the microtest modification of the rapid fluorescent focus inhibition test before and after primary vaccination in 30 puppies, and before and after booster vaccination in 59 previously vaccinated dogs. A commercial modified live virus vaccine was used. Three weeks after primary vaccination the mean antibody titre was 102 +/- 90, but only 24 dogs presented for booster vaccination had detectable antibody levels (mean titre 12 +/- 16). The antibody responses three weeks after booster vaccination (mean 380 +/- 216) were significantly greater than the responses to primary vaccination. It was concluded that previously vaccinated dogs could have an anamnestic response to booster vaccination, even when antibodies were not detected in their sera before revaccination.
在一项现场研究中，采用快速荧光灶抑制试验的微量试验改良法，测定了30只幼犬初次接种疫苗前后以及59只先前已接种疫苗的犬再次接种疫苗前后的狂犬病病毒中和抗体效价。使用的是一种商业性改良活病毒疫苗。初次接种疫苗三周后，平均抗体效价为102±90，但只有24只前来进行再次接种的犬具有可检测到的抗体水平（平均效价12±16）。再次接种疫苗三周后的抗体反应（平均380±216）显著高于初次接种疫苗后的反应。得出的结论是，先前已接种疫苗的犬即使在再次接种疫苗前血清中未检测到抗体，对再次接种疫苗也可能产生回忆反应。
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