Genetzky R M, Hagemoser W A
Can Vet J. 1985 Dec;26(12):391-5.
Two mature horses were examined for changes in laboratory and physical findings after experimentally induced bladder rupture. The postrupture laboratory diagnostic changes, which provide valuable information for a correct diagnosis are described. Hematology, serum and peritoneal fluid sodium, potassium, calcium, phosphorous, creatinine, urea nitrogen, albumin and peritoneal fluid components were measured and evaluated versus time. Hyponatremia and hyperkalemia occurred, as well as increased concentrations of peritoneal fluid potassium and inorganic phosphorus. In addition, peritoneal fluid creatinine:serum creatinine and peritoneal fluid urea nitrogen:serum urea nitrogen ratios were followed with time. Hematology and cytology of the peritoneal fluid showed an inflammatory response to urine contamination of the abdominal cavity. Physical findings of tachypnea and tachycardia as well as a mild colic were absent until nearly 50 hours postrupture. Based on these findings, it was concluded that the peritoneal fluid creatinine:serum creatinine ratio was the most useful antemortem laboratory diagnostic aid.
对两匹成年马进行实验性诱导膀胱破裂，观察其实验室检查和体格检查结果的变化。描述了破裂后的实验室诊断变化，这些变化为正确诊断提供了有价值的信息。对血液学、血清和腹腔液中的钠、钾、钙、磷、肌酐、尿素氮、白蛋白以及腹腔液成分进行了测量，并随时间进行评估。出现了低钠血症和高钾血症，同时腹腔液中钾和无机磷的浓度增加。此外，还跟踪观察了腹腔液肌酐：血清肌酐和腹腔液尿素氮：血清尿素氮的比值随时间的变化。血液学和腹腔液细胞学检查显示对腹腔尿液污染有炎症反应。直到破裂后近50小时，才出现呼吸急促、心动过速以及轻度绞痛等体格检查结果。基于这些发现，得出结论：腹腔液肌酐：血清肌酐比值是最有用的生前实验室诊断辅助指标。
