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猫胃肠道腺癌:综述与回顾性研究

Feline gastrointestinal adenocarcinoma: a review and retrospective study.

作者信息

Cribb A E

出版信息

Can Vet J. 1988 Sep;29(9):709-12.

PMID:17423115
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1680855/
Abstract

Feline gastrointestinal adenocarcinomas are the most common nonhematopoietic gastrointestinal tumors in cats. They are highly malignant tumors causing intestinal obstruction due to the annular, stenosing nature to their growth. Current literature is largely based on surveys of pathology records. Therefore, a retrospective study was conducted to evaluate clinical course and prognosis with surgical excision of the tumor. In published reports feline gastrointestinal adenocarcinoma represented 20-35% of gastrointestinal neoplasia in the cat; the average age was greater than ten years; and there was a greater incidence in Siamese. The small intestine accounted for 70% of cases. In this retrospective study, cats usually had a long history of non-specific gastrointestinal disease; weight loss and vomiting were the most common signs. Abdominal radiographs demonstrate intestinal obstruction, and an abdominal mass is often palpable. With intestinal resection and anastomosis, median survival time was 2.5 months (range: 0-24 months). Tubular adenocarcinomas may have a better prognosis than other histological types, especially if metastasis is not present at the time of surgery. A significant disease-free interval is possible in some cases.

摘要

猫胃肠道腺癌是猫最常见的非造血性胃肠道肿瘤。它们是高度恶性肿瘤,因其呈环形、狭窄性生长而导致肠梗阻。目前的文献主要基于病理记录调查。因此,进行了一项回顾性研究,以评估手术切除肿瘤后的临床病程和预后。在已发表的报告中,猫胃肠道腺癌占猫胃肠道肿瘤的20%-35%;平均年龄超过10岁;暹罗猫的发病率更高。小肠占病例的70%。在这项回顾性研究中,猫通常有长期的非特异性胃肠道疾病史;体重减轻和呕吐是最常见的症状。腹部X光片显示肠梗阻,腹部肿块常可触及。行肠切除吻合术后,中位生存时间为2.5个月(范围:0-24个月)。管状腺癌的预后可能比其他组织学类型更好,尤其是在手术时没有转移的情况下。在某些情况下,可能有显著的无病间期。

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引用本文的文献

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Outcome and Prognostic Factors in Cats Undergoing Resection of Intestinal Adenocarcinomas: 58 Cases (2008-2020).接受肠腺癌切除术的猫的预后及预后因素:58例病例(2008 - 2020年)
Front Vet Sci. 2022 Jun 27;9:911666. doi: 10.3389/fvets.2022.911666. eCollection 2022.
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Preliminary study of CT features of intermediate- and high-grade alimentary lymphoma and adenocarcinoma in cats.猫的中高级胃肠道淋巴瘤和腺癌的 CT 特征初步研究。
J Feline Med Surg. 2022 Oct;24(10):1065-1071. doi: 10.1177/1098612X211046847. Epub 2021 Oct 19.
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J Vet Intern Med. 2018 May;32(3):1178-1184. doi: 10.1111/jvim.15099. Epub 2018 Mar 23.
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Surgical versus non-surgical treatment of feline small intestinal adenocarcinoma and the influence of metastasis on long-term survival in 18 cats (2000-2007).
Can Vet J. 2011 Oct;52(10):1101-5.
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Gastroduodenal ulceration in cats: eight cases and a review of the literature.猫胃十二指肠溃疡:八例病例及文献综述
J Feline Med Surg. 2002 Mar;4(1):27-42. doi: 10.1053/jfms.2001.0148.
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