Immune response of the Mongolian gerbil (Meriones unguiculatus) to sheep red blood cells.
作者信息
Yukawa M, Onodera T, Yoshihara K, Saitoh H, Mochizuki K
机构信息
Laboratory of Biomedical Science, College of Agriculture and Veterinary Medicine, Nihon University, Tsukuba, Japan.
出版信息
J Exp Anim Sci. 1991;34(3):87-92.
The immune responses of Mongolian gerbils, Meriones unguiculatus, to sheep red blood cells (SRBC) were studied as compared to those of mice. After a single injection of SRBC, hemagglutinin titers in gerbils were significantly lower and hemolytic plaque-forming cells (PFC) in the spleen were less in number as compared to the response of mice. In gerbils the PFC response to a higher dose of bacterial lipopolysaccharide (LPS) was rather higher than in mice. The delayed-type hypersensitivity (DTH) assay on the foot-pad revealed that the responsiveness was considerably lower in gerbils than in mice.
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