Hutchison T W, Riddell C
Can Vet J. 1990 Jan;31(1):20-5.
A detailed descriptive study was done on broiler chickens with abnormal livers found at processing. Two syndromes were evident: those birds with enlarged, pale, firm livers, designated hepatosis, with Clostridium perfringens type A often isolated; and ascitic birds with cobblestone-appearing livers. Livers with hepatosis had marked proliferation of bile ducts; ascitic livers had normal architecture. Hearts from birds with ascites had elevated right ventricular/total ventricular weight ratios, whereas hearts from normal birds and birds with hepatosis did not. Two isolates of C. perfringens produced necrotic enteritis in experimental birds; an attempt to reproduce hepatosis with these isolates was unsuccessful.
对加工时发现肝脏异常的肉鸡进行了详细的描述性研究。有两种综合征很明显：一种是肝脏肿大、苍白、坚硬的鸡，称为肝病，常分离出A型产气荚膜梭菌；另一种是肝脏呈鹅卵石样的腹水鸡。患肝病的鸡肝脏胆管显著增生；腹水鸡的肝脏结构正常。腹水鸡的心脏右心室/全心室重量比升高，而正常鸡和患肝病鸡的心脏则没有。两株产气荚膜梭菌在实验鸡中引发了坏死性肠炎；用这些菌株重现肝病的尝试未成功。
