Prince Steven E, Tsukiura Takashi, Cabeza Roberto
Center for Cognitive Neuroscience, Duke University, Durham, NC 27708, USA.
Psychol Sci. 2007 Feb;18(2):144-51. doi: 10.1111/j.1467-9280.2007.01864.x.
Episodic memory and semantic memory interact very closely. In particular, episodic memory encoding (EE) tends to elicit semantic memory retrieval (SR), and vice versa. Thus, similar activations for EE and SR in functional neuroimaging studies may reflect shared memory processes, or they may reflect the fact that EE and SR are usually confounded. To address this issue, we used a factorial functional magnetic resonance imaging approach to disentangle the neural correlates of EE and SR. Within the left temporal lobe, the hippocampus was associated with successful EE, whereas a posterior lateral region was associated with successful SR. Within the left inferior prefrontal cortex, a posterior region was involved in SR, a mid region was involved in both SR and EE, and an anterior region was involved in EE, but only when SR was also high. Thus, the neural correlates of EE and SR are dissociable but interact in specific brain regions.
情景记忆和语义记忆密切相互作用。具体而言，情景记忆编码（EE）往往会引发语义记忆提取（SR），反之亦然。因此，在功能神经影像学研究中，EE和SR的类似激活可能反映了共享的记忆过程，或者它们可能反映了EE和SR通常相互混淆的事实。为了解决这个问题，我们使用了析因功能磁共振成像方法来区分EE和SR的神经关联。在左侧颞叶内，海马体与成功的EE相关，而后外侧区域与成功的SR相关。在左侧前额叶下回皮质内，后部区域参与SR，中部区域同时参与SR和EE，前部区域参与EE，但仅当SR也很高时才参与。因此，EE和SR的神经关联是可分离的，但在特定脑区相互作用。
